Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 314270..315070 Replicon chromosome
Accession NZ_CP117647
Organism Escherichia albertii strain BIA_16-3

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag PS048_RS01495 Protein ID WP_273785535.1
Coordinates 314543..315070 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A8H9C3F4
Locus tag PS048_RS01490 Protein ID WP_001277105.1
Coordinates 314270..314536 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS048_RS01465 (309991) 309991..310845 - 855 WP_000370584.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
PS048_RS01470 (310838) 310838..311584 - 747 WP_000151888.1 PTS sugar transporter subunit IIC -
PS048_RS01475 (311601) 311601..312086 - 486 WP_000029259.1 PTS sugar transporter subunit IIB -
PS048_RS01480 (312093) 312093..312494 - 402 WP_273785531.1 PTS sugar transporter subunit IIA -
PS048_RS01485 (313017) 313017..314120 + 1104 WP_010319184.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS048_RS01490 (314270) 314270..314536 + 267 WP_001277105.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS048_RS01495 (314543) 314543..315070 + 528 WP_273785535.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS048_RS01500 (315067) 315067..315450 - 384 WP_000778774.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS048_RS01505 (315874) 315874..316983 + 1110 WP_000827693.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS048_RS01510 (317031) 317031..317957 + 927 WP_001295111.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS048_RS01515 (317954) 317954..319231 + 1278 WP_059225128.1 branched chain amino acid ABC transporter permease LivM -
PS048_RS01520 (319228) 319228..319995 + 768 WP_044709901.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(2-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19679.53 Da        Isoelectric Point: 6.3293

>T271845 WP_273785535.1 NZ_CP117647:314543-315070 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCSNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQEQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9935.40 Da        Isoelectric Point: 9.2494

>AT271845 WP_001277105.1 NZ_CP117647:314270-314536 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNCASQRAAEVIEQNRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References