Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 298437..299237 Replicon chromosome
Accession NZ_CP117643
Organism Escherichia albertii strain BIA_17

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag PS043_RS01405 Protein ID WP_161537617.1
Coordinates 298710..299237 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PS043_RS01400 Protein ID WP_001277104.1
Coordinates 298437..298703 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS043_RS01375 (294232) 294232..294978 - 747 WP_000151888.1 PTS sugar transporter subunit IIC -
PS043_RS01380 (295131) 295131..295828 + 698 WP_094096600.1 IS1-like element IS1A family transposase -
PS043_RS01385 (295763) 295763..296257 - 495 WP_273816710.1 PTS sugar transporter subunit IIB -
PS043_RS01390 (296264) 296264..296665 - 402 WP_001071334.1 PTS sugar transporter subunit IIA -
PS043_RS01395 (297184) 297184..298287 + 1104 WP_273816711.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS043_RS01400 (298437) 298437..298703 + 267 WP_001277104.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS043_RS01405 (298710) 298710..299237 + 528 WP_161537617.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS043_RS01410 (299234) 299234..299617 - 384 WP_113640799.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS043_RS01415 (300041) 300041..300247 + 207 Protein_279 ABC transporter substrate-binding protein -
PS043_RS01420 (300303) 300303..301000 + 698 WP_094096600.1 IS1-like element IS1A family transposase -
PS043_RS01425 (301016) 301016..301927 + 912 Protein_281 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS043_RS01430 (301975) 301975..302901 + 927 WP_029400061.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS043_RS01435 (302898) 302898..304175 + 1278 WP_161537618.1 branched chain amino acid ABC transporter permease LivM -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 295131..312241 17110
- inside IScluster/Tn - - 295131..301000 5869


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(90-150)

Antitoxin

(8-86)


Sequences


Toxin        


Download         Length: 176 a.a.        Molecular weight: 19648.52 Da        Isoelectric Point: 6.9585

>T271816 WP_161537617.1 NZ_CP117643:298710-299237 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCRNTPERQALGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9958.44 Da        Isoelectric Point: 9.2519

>AT271816 WP_001277104.1 NZ_CP117643:298437-298703 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNCASQRAAEVIEQHRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References