Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ataRT/DUF1778(antitoxin) |
Location | 298437..299237 | Replicon | chromosome |
Accession | NZ_CP117643 | ||
Organism | Escherichia albertii strain BIA_17 |
Toxin (Protein)
Gene name | ataT | Uniprot ID | - |
Locus tag | PS043_RS01405 | Protein ID | WP_161537617.1 |
Coordinates | 298710..299237 (+) | Length | 176 a.a. |
Antitoxin (Protein)
Gene name | ataR | Uniprot ID | - |
Locus tag | PS043_RS01400 | Protein ID | WP_001277104.1 |
Coordinates | 298437..298703 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PS043_RS01375 (294232) | 294232..294978 | - | 747 | WP_000151888.1 | PTS sugar transporter subunit IIC | - |
PS043_RS01380 (295131) | 295131..295828 | + | 698 | WP_094096600.1 | IS1-like element IS1A family transposase | - |
PS043_RS01385 (295763) | 295763..296257 | - | 495 | WP_273816710.1 | PTS sugar transporter subunit IIB | - |
PS043_RS01390 (296264) | 296264..296665 | - | 402 | WP_001071334.1 | PTS sugar transporter subunit IIA | - |
PS043_RS01395 (297184) | 297184..298287 | + | 1104 | WP_273816711.1 | branched chain amino acid ABC transporter substrate-binding protein LivJ | - |
PS043_RS01400 (298437) | 298437..298703 | + | 267 | WP_001277104.1 | type II toxin-antitoxin system antitoxin AtaR | Antitoxin |
PS043_RS01405 (298710) | 298710..299237 | + | 528 | WP_161537617.1 | type II toxin-antitoxin system toxin acetyltransferase AtaT | Toxin |
PS043_RS01410 (299234) | 299234..299617 | - | 384 | WP_113640799.1 | aspartate 1-decarboxylase autocleavage activator PanM | - |
PS043_RS01415 (300041) | 300041..300247 | + | 207 | Protein_279 | ABC transporter substrate-binding protein | - |
PS043_RS01420 (300303) | 300303..301000 | + | 698 | WP_094096600.1 | IS1-like element IS1A family transposase | - |
PS043_RS01425 (301016) | 301016..301927 | + | 912 | Protein_281 | high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK | - |
PS043_RS01430 (301975) | 301975..302901 | + | 927 | WP_029400061.1 | high-affinity branched-chain amino acid ABC transporter permease LivH | - |
PS043_RS01435 (302898) | 302898..304175 | + | 1278 | WP_161537618.1 | branched chain amino acid ABC transporter permease LivM | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 295131..312241 | 17110 | |
- | inside | IScluster/Tn | - | - | 295131..301000 | 5869 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 176 a.a. Molecular weight: 19648.52 Da Isoelectric Point: 6.9585
>T271816 WP_161537617.1 NZ_CP117643:298710-299237 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCRNTPERQALGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCRNTPERQALGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD
Download Length: 528 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|