Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 4202396..4203069 Replicon chromosome
Accession NZ_CP117637
Organism Escherichia albertii strain BIA_18

Toxin (Protein)


Gene name ykfI Uniprot ID A0A8H9EW26
Locus tag PS040_RS20770 Protein ID WP_059273492.1
Coordinates 4202396..4202737 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PS040_RS20775 Protein ID WP_273783921.1
Coordinates 4202758..4203069 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS040_RS20755 (4199396) 4199396..4199953 - 558 WP_000955766.1 hypothetical protein -
PS040_RS20760 (4200284) 4200284..4200820 - 537 WP_059221727.1 hypothetical protein -
PS040_RS20765 (4201125) 4201125..4202132 - 1008 WP_059273491.1 restriction endonuclease -
PS040_RS20770 (4202396) 4202396..4202737 - 342 WP_059273492.1 TA system toxin CbtA family protein Toxin
PS040_RS20775 (4202758) 4202758..4203069 - 312 WP_273783921.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PS040_RS20780 (4203109) 4203109..4203650 - 542 Protein_4064 DNA repair protein RadC -
PS040_RS20785 (4203663) 4203663..4204103 - 441 WP_059273494.1 antirestriction protein -
PS040_RS20790 (4204134) 4204134..4204373 - 240 Protein_4066 DUF932 domain-containing protein -
PS040_RS20795 (4204413) 4204413..4204637 + 225 WP_236926507.1 AlpA family transcriptional regulator -
PS040_RS20800 (4205059) 4205059..4207134 + 2076 WP_059273495.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - vat / nleE / nleB1 4190068..4208853 18785


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(5-102)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12778.74 Da        Isoelectric Point: 8.0324

>T271807 WP_059273492.1 NZ_CP117637:c4202737-4202396 [Escherichia albertii]
MKTLPATTPQAVTLCLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNFLVEKYGLVRIDRRGF
DWQEQSPYLRAVDILRARQTTGLLKRNRISAAR

Download         Length: 342 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11555.99 Da        Isoelectric Point: 6.0543

>AT271807 WP_273783921.1 NZ_CP117637:c4203069-4202758 [Escherichia albertii]
ISPVGLNRNVTPCFGARLVQEGNRLHYLVDRASITGEFSNAESLKLDEVFPHFISQMESMLTTGEMNPRYAHCVTLYHNG
FTCEADTLGSYGYVYSAVYPTQR

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References