Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 285245..286045 Replicon chromosome
Accession NZ_CP117637
Organism Escherichia albertii strain BIA_18

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag PS040_RS01330 Protein ID WP_273782756.1
Coordinates 285518..286045 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PS040_RS01325 Protein ID WP_001277104.1
Coordinates 285245..285511 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS040_RS01300 (280966) 280966..281820 - 855 WP_273782751.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
PS040_RS01305 (281813) 281813..282559 - 747 WP_000151888.1 PTS sugar transporter subunit IIC -
PS040_RS01310 (282576) 282576..283061 - 486 WP_000029259.1 PTS sugar transporter subunit IIB -
PS040_RS01315 (283068) 283068..283469 - 402 WP_273782753.1 PTS sugar transporter subunit IIA -
PS040_RS01320 (283992) 283992..285095 + 1104 WP_010319184.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS040_RS01325 (285245) 285245..285511 + 267 WP_001277104.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS040_RS01330 (285518) 285518..286045 + 528 WP_273782756.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS040_RS01335 (286042) 286042..286425 - 384 WP_059270572.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS040_RS01340 (286849) 286849..287958 + 1110 WP_000827693.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS040_RS01345 (288006) 288006..288932 + 927 WP_001295097.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS040_RS01350 (288929) 288929..290206 + 1278 WP_059218996.1 branched chain amino acid ABC transporter permease LivM -
PS040_RS01355 (290203) 290203..290970 + 768 WP_059218997.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19539.45 Da        Isoelectric Point: 6.3254

>T271790 WP_273782756.1 NZ_CP117637:285518-286045 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCSNTPECQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYLSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9958.44 Da        Isoelectric Point: 9.2519

>AT271790 WP_001277104.1 NZ_CP117637:285245-285511 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNCASQRAAEVIEQHRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References