Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 25513..26035 Replicon plasmid pEA22_1
Accession NZ_CP117629
Organism Escherichia albertii strain BIA_22

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PS041_RS24495 Protein ID WP_065106543.1
Coordinates 25754..26035 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PS041_RS24490 Protein ID WP_273818005.1
Coordinates 25513..25764 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS041_RS24475 (21868) 21868..21963 + 96 WP_000609147.1 DinQ-like type I toxin DqlB -
PS041_RS24480 (22180) 22180..23342 + 1163 WP_273825565.1 IS3 family transposase -
PS041_RS24485 (23540) 23540..24376 - 837 WP_273818004.1 replication initiation protein -
PS041_RS24490 (25513) 25513..25764 + 252 WP_273818005.1 plasmid stabilization protein Antitoxin
PS041_RS24495 (25754) 25754..26035 + 282 WP_065106543.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PS041_RS24500 (26414) 26414..27591 - 1178 Protein_22 IS91 family transposase -
PS041_RS24505 (27591) 27591..27956 - 366 WP_273818006.1 hypothetical protein -
PS041_RS24510 (28118) 28118..28594 + 477 WP_273818007.1 CesD/SycD/LcrH family type III secretion system chaperone -
PS041_RS24515 (28619) 28619..29317 + 699 WP_273825566.1 hypothetical protein -
PS041_RS24520 (29748) 29748..30182 + 435 Protein_26 transposase -
PS041_RS24525 (30221) 30221..30316 - 96 Protein_27 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid sitABCD vat / vat / nleA/espI / espK / iutA / iucD / iucC / iucB / iucA 1..152064 152064
- inside IScluster/Tn - - 15236..37668 22432


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11021.83 Da        Isoelectric Point: 10.5938

>T271775 WP_065106543.1 NZ_CP117629:25754-26035 [Escherichia albertii]
MTYELAFDRRALKEWQKLGHTIREQFKKKLSERLENPRVPAARLHGHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGR
RESSEVYQIADLR

Download         Length: 282 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9109.36 Da        Isoelectric Point: 4.2558

>AT271775 WP_273818005.1 NZ_CP117629:25513-25764 [Escherichia albertii]
MSYQILTTTAASITDLKKNPMGTVAEGEGGAVAILNRNEPAFYCVPPKLYAYYRELAEDAELNAVADERMKNPEIVKVSL
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References