Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 539516..540092 Replicon chromosome
Accession NZ_CP117628
Organism Escherichia albertii strain BIA_22

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag PS041_RS02710 Protein ID WP_024164652.1
Coordinates 539516..539803 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag PS041_RS02715 Protein ID WP_000063163.1
Coordinates 539790..540092 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS041_RS02695 (535081) 535081..536481 - 1401 WP_059254411.1 restriction endonuclease subunit S -
PS041_RS02700 (536471) 536471..538090 - 1620 WP_044717122.1 class I SAM-dependent DNA methyltransferase -
PS041_RS02705 (538154) 538154..539319 - 1166 Protein_523 restriction endonuclease -
PS041_RS02710 (539516) 539516..539803 + 288 WP_024164652.1 BrnT family toxin Toxin
PS041_RS02715 (539790) 539790..540092 + 303 WP_000063163.1 BrnA antitoxin family protein Antitoxin
PS041_RS02720 (540126) 540126..541082 - 957 WP_273824881.1 GTPase -
PS041_RS02725 (541093) 541093..541296 - 204 WP_000467859.1 YbdD/YjiX family protein -
PS041_RS02730 (541416) 541416..543566 - 2151 WP_273824883.1 pyruvate/proton symporter BtsT -
PS041_RS02735 (544088) 544088..544386 + 299 Protein_529 Tar ligand binding domain-containing protein -
PS041_RS02740 (544410) 544410..544541 + 132 WP_024164650.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(37-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11128.57 Da        Isoelectric Point: 6.9903

>T271759 WP_024164652.1 NZ_CP117628:539516-539803 [Escherichia albertii]
MPMEFEWDANKAKSNQVKHGIRFEDAVLVFDDPQHLSQQDRIENGEYRWQTIGLVHGIVVILVAHTIRFESGNEIIRIIS
ARKADRKERSRYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11541.03 Da        Isoelectric Point: 9.8217

>AT271759 WP_000063163.1 NZ_CP117628:539790-540092 [Escherichia albertii]
MSMVKHKRGTSSTLDVQREAELKALANKSDEDIDYSDIPPSSDEQWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References