Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 4331237..4332037 Replicon chromosome
Accession NZ_CP117620
Organism Escherichia albertii strain BIA_24

Toxin (Protein)


Gene name ataT Uniprot ID A0A8H9C5V7
Locus tag PS039_RS21075 Protein ID WP_000342455.1
Coordinates 4331237..4331764 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PS039_RS21080 Protein ID WP_273809817.1
Coordinates 4331771..4332037 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS039_RS21050 (4326312) 4326312..4327079 - 768 WP_000082094.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -
PS039_RS21055 (4327076) 4327076..4328353 - 1278 WP_273809813.1 branched chain amino acid ABC transporter permease LivM -
PS039_RS21060 (4328350) 4328350..4329276 - 927 WP_001295097.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS039_RS21065 (4329324) 4329324..4330433 - 1110 WP_273809815.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS039_RS21070 (4330857) 4330857..4331240 + 384 WP_000778774.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS039_RS21075 (4331237) 4331237..4331764 - 528 WP_000342455.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS039_RS21080 (4331771) 4331771..4332037 - 267 WP_273809817.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS039_RS21085 (4332187) 4332187..4333290 - 1104 WP_010319184.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS039_RS21090 (4333809) 4333809..4334210 + 402 WP_001071334.1 PTS sugar transporter subunit IIA -
PS039_RS21095 (4334217) 4334217..4334702 + 486 WP_000029259.1 PTS sugar transporter subunit IIB -
PS039_RS21100 (4334719) 4334719..4335465 + 747 WP_000151888.1 PTS sugar transporter subunit IIC -
PS039_RS21105 (4335458) 4335458..4336312 + 855 WP_273809820.1 PTS system mannose/fructose/sorbose family transporter subunit IID -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19607.47 Da        Isoelectric Point: 6.6343

>T271747 WP_000342455.1 NZ_CP117620:c4331764-4331237 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCSNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9942.37 Da        Isoelectric Point: 10.0863

>AT271747 WP_273809817.1 NZ_CP117620:c4332037-4331771 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQHRRMILNEESWTRVMDALSNPPSPGEKIKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References