Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1163562..1164229 Replicon chromosome
Accession NZ_CP117609
Organism Escherichia albertii strain BIA_26

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag PS038_RS05585 Protein ID WP_059219247.1
Coordinates 1163562..1163891 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PS038_RS05590 Protein ID WP_059219248.1
Coordinates 1163912..1164229 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS038_RS05560 (1159633) 1159633..1159767 + 135 WP_265349177.1 hypothetical protein -
PS038_RS05565 (1160286) 1160286..1160867 + 582 WP_000062487.1 hypothetical protein -
PS038_RS05570 (1160974) 1160974..1161309 - 336 Protein_1089 IS200/IS605 family transposase -
PS038_RS05575 (1161829) 1161829..1162509 + 681 WP_059219246.1 site-specific DNA-methyltransferase -
PS038_RS05580 (1162804) 1162804..1163154 - 351 Protein_1091 integrase arm-type DNA-binding domain-containing protein -
PS038_RS05585 (1163562) 1163562..1163891 - 330 WP_059219247.1 TA system toxin CbtA family protein Toxin
PS038_RS05590 (1163912) 1163912..1164229 - 318 WP_059219248.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PS038_RS05595 (1164247) 1164247..1164468 - 222 WP_059219249.1 DUF987 domain-containing protein -
PS038_RS05600 (1164477) 1164477..1164953 - 477 WP_059219250.1 RadC family protein -
PS038_RS05605 (1164969) 1164969..1165358 - 390 Protein_1096 antirestriction protein -
PS038_RS05610 (1166738) 1166738..1167031 + 294 WP_059219254.1 hypothetical protein -
PS038_RS05615 (1167324) 1167324..1167842 + 519 WP_059219255.1 hypothetical protein -
PS038_RS05620 (1168002) 1168002..1168987 + 986 Protein_1099 IS3-like element IS911 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1161829..1176591 14762


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12301.22 Da        Isoelectric Point: 9.9589

>T271678 WP_059219247.1 NZ_CP117609:c1163891-1163562 [Escherichia albertii]
MKPQPATTSRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSTETTIREHIDAGISLSDAVNFLVEKYGLVRIDRKGF
SWQEQTPYISVVDILRARRSTGLLKTNVK

Download         Length: 330 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11771.41 Da        Isoelectric Point: 7.3229

>AT271678 WP_059219248.1 NZ_CP117609:c1164229-1163912 [Escherichia albertii]
MSNITWGLQRGITPRLGARLVQEGNRLHYLADRASITGKFSDAECLKLDVAFPHFISQMESMLTTGDMNPRHAHCVPLYH
SGFTCESDTFGSCGYVYIAIYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References