Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2783187..2783838 Replicon chromosome
Accession NZ_CP117606
Organism Escherichia albertii strain BIA_29

Toxin (Protein)


Gene name cptA Uniprot ID B1EG01
Locus tag PS031_RS13615 Protein ID WP_000244763.1
Coordinates 2783187..2783591 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag PS031_RS13620 Protein ID WP_059224144.1
Coordinates 2783572..2783838 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS031_RS13595 (2779150) 2779150..2780883 - 1734 WP_000813238.1 single-stranded-DNA-specific exonuclease RecJ -
PS031_RS13600 (2780889) 2780889..2781599 - 711 WP_000748106.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PS031_RS13605 (2781624) 2781624..2782520 - 897 WP_000806638.1 site-specific tyrosine recombinase XerD -
PS031_RS13610 (2782632) 2782632..2783153 + 522 WP_059221135.1 flavodoxin FldB -
PS031_RS13615 (2783187) 2783187..2783591 - 405 WP_000244763.1 protein YgfX Toxin
PS031_RS13620 (2783572) 2783572..2783838 - 267 WP_059224144.1 FAD assembly factor SdhE Antitoxin
PS031_RS13625 (2783828) 2783828..2784058 - 231 WP_059224142.1 hypothetical protein -
PS031_RS13630 (2784090) 2784090..2785070 + 981 WP_059224140.1 tRNA-modifying protein YgfZ -
PS031_RS13635 (2785511) 2785511..2786170 - 660 WP_000250281.1 hemolysin III family protein -
PS031_RS13640 (2786338) 2786338..2786649 - 312 WP_098401332.1 N(4)-acetylcytidine aminohydrolase -
PS031_RS13645 (2786694) 2786694..2788127 + 1434 WP_024164724.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15888.81 Da        Isoelectric Point: 11.1732

>T271655 WP_000244763.1 NZ_CP117606:c2783591-2783187 [Escherichia albertii]
VVLWQSDLRVSWRAQWLSLLIHGLVAAAILLMPWPLSYTPLWMVLLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQ
EWSIVRAPWMIKTGMMLRLLSDSGKRQHLWLAADSMDEAEWRDLRRILLQQEIQ

Download         Length: 405 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10575.17 Da        Isoelectric Point: 5.1599

>AT271655 WP_059224144.1 NZ_CP117606:c2783838-2783572 [Escherichia albertii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFIRLLECDDPDLFNWLMNHGKPVDAELEMMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S6P9B3

Antitoxin

Source ID Structure

References