Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1953942..1954213 Replicon chromosome
Accession NC_017625
Organism Escherichia coli DH1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1954072..1954175 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1953942..1954213 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECDH1_RS09550 1950497..1951159 - 663 WP_000944256.1 exodeoxyribonuclease X -
ECDH1_RS09555 1951183..1951839 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
ECDH1_RS09560 1951941..1952171 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ECDH1_RS09565 1952310..1952684 + 375 WP_000168747.1 CopC domain-containing protein YobA -
ECDH1_RS09570 1952688..1953560 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
ECDH1_RS09575 1953573..1953914 + 342 WP_000976476.1 YebY family protein -
- 1953942..1954213 - 272 - - Antitoxin
- 1954072..1954175 + 104 - - Toxin
ECDH1_RS09585 1954310..1954966 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
ECDH1_RS09590 1954967..1955158 - 192 WP_000457842.1 YebW family protein -
ECDH1_RS09595 1955263..1955499 - 237 WP_001295499.1 DUF1480 family protein -
ECDH1_RS09600 1955617..1957056 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T27162 NC_017625:1954072-1954175 [Escherichia coli DH1]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT27162 NC_017625:c1954213-1953942 [Escherichia coli DH1]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References