Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4129975..4130570 Replicon chromosome
Accession NZ_CP117595
Organism Escherichia albertii strain BIA_35

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag PS050_RS19910 Protein ID WP_059255551.1
Coordinates 4129975..4130325 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag PS050_RS19915 Protein ID WP_059255553.1
Coordinates 4130319..4130570 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS050_RS19890 (4125580) 4125580..4126548 + 969 WP_273818859.1 PfkB family carbohydrate kinase -
PS050_RS19895 (4126562) 4126562..4127944 + 1383 WP_137653529.1 sugar porter family MFS transporter -
PS050_RS19900 (4128030) 4128030..4128530 + 501 WP_059255546.1 D-ribose pyranase -
PS050_RS19905 (4128543) 4128543..4129922 + 1380 WP_137650500.1 sugar porter family MFS transporter -
PS050_RS19910 (4129975) 4129975..4130325 - 351 WP_059255551.1 type II toxin-antitoxin system ChpB family toxin Toxin
PS050_RS19915 (4130319) 4130319..4130570 - 252 WP_059255553.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PS050_RS19920 (4130779) 4130779..4131123 - 345 WP_001219163.1 gamma-glutamylcyclotransferase -
PS050_RS19925 (4131126) 4131126..4134905 - 3780 WP_141109352.1 autotransporter assembly complex protein TamB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12631.65 Da        Isoelectric Point: 5.1420

>T271610 WP_059255551.1 NZ_CP117595:c4130325-4129975 [Escherichia albertii]
MVKRSEFERGDIMLVGFDPASGHEQRGAGRPVLVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLRCEEGDVCGVVVV
NQVRMMDLNARQAKRIGLACDEVVEEVLLRLQAVVE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9237.69 Da        Isoelectric Point: 4.9431

>AT271610 WP_059255553.1 NZ_CP117595:c4130570-4130319 [Escherichia albertii]
MRITIKKWGNSAGMVIPNIVMKGLKLQPGQSLEAQVRNNQLILTPVSKRYSLDELLAQCDMNAPELSEQDVWGTLSPAGD
EIW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References