Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 80653..81200 Replicon plasmid pEA36_2
Accession NZ_CP117592
Organism Escherichia albertii strain BIA_36

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PS051_RS24710 Protein ID WP_265099691.1
Coordinates 80653..80931 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID Q5JBQ7
Locus tag PS051_RS24715 Protein ID WP_000079943.1
Coordinates 80931..81200 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS051_RS24690 (75830) 75830..76528 + 699 WP_273782076.1 DUF554 domain-containing protein -
PS051_RS24695 (76622) 76622..77167 + 546 WP_273782086.1 isopentenyl-diphosphate Delta-isomerase -
PS051_RS24700 (77334) 77334..79088 + 1755 WP_273782077.1 tannase/feruloyl esterase family alpha/beta hydrolase -
PS051_RS24705 (80137) 80137..80439 + 303 WP_233929319.1 hypothetical protein -
PS051_RS24710 (80653) 80653..80931 - 279 WP_265099691.1 type II toxin-antitoxin system toxin YacB Toxin
PS051_RS24715 (80931) 80931..81200 - 270 WP_000079943.1 type II toxin-antitoxin system antitoxin YacA Antitoxin
PS051_RS24720 (81482) 81482..82162 - 681 WP_233929282.1 nitroreductase -
PS051_RS24725 (82422) 82422..83471 - 1050 WP_273782078.1 alpha/beta hydrolase -
PS051_RS24730 (83722) 83722..84888 + 1167 WP_233929281.1 aldo/keto reductase -
PS051_RS24735 (84903) 84903..85583 + 681 WP_233929280.1 heavy metal response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..89679 89679


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10804.46 Da        Isoelectric Point: 9.4120

>T271589 WP_265099691.1 NZ_CP117592:c80931-80653 [Escherichia albertii]
MEIFWTMLASQDRKRIREYIAERNLMAAIELDERIGYSASTLAGQPYKGRNGRVEGTRELVIHPHFVLVYEVDSQWGKVY
ILRVLHTAQKWP

Download         Length: 279 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10272.57 Da        Isoelectric Point: 7.2057

>AT271589 WP_000079943.1 NZ_CP117592:c81200-80931 [Escherichia albertii]
MAQVNMSLRIDAELKDAFMAAAKSMDRNGSQLIRDFMRQTVERQHNTWFRDQVEAGRQQLERGDVLSHDMVESSATAWRD
EMSRKVAGK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A622US83

References