Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 61101..61726 Replicon plasmid pEA36_2
Accession NZ_CP117592
Organism Escherichia albertii strain BIA_36

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PS051_RS24590 Protein ID WP_000911317.1
Coordinates 61328..61726 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PS051_RS24585 Protein ID WP_021541611.1
Coordinates 61101..61328 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS051_RS24585 (61101) 61101..61328 + 228 WP_021541611.1 toxin-antitoxin system antitoxin VapB Antitoxin
PS051_RS24590 (61328) 61328..61726 + 399 WP_000911317.1 type II toxin-antitoxin system VapC family toxin Toxin
PS051_RS24595 (61735) 61735..62586 - 852 Protein_64 type IV secretion system DNA-binding domain-containing protein -
PS051_RS24600 (62581) 62581..62703 - 123 Protein_65 hypothetical protein -
PS051_RS24605 (63279) 63279..63416 - 138 Protein_66 hypothetical protein -
PS051_RS24610 (63837) 63837..64085 + 249 WP_032084478.1 DinI-like family protein -
PS051_RS24615 (64133) 64133..64519 + 387 WP_001462441.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
PS051_RS24620 (64519) 64519..65793 + 1275 WP_233929288.1 translesion error-prone DNA polymerase V subunit UmuC -
PS051_RS24625 (65795) 65795..66211 - 417 WP_001278818.1 plasmid partitioning/stability family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..89679 89679


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14857.14 Da        Isoelectric Point: 8.5264

>T271587 WP_000911317.1 NZ_CP117592:61328-61726 [Escherichia albertii]
MLKFMLDTNICIFTIKNKPASVRERFNLNQGRMCISSVTLMELIYGAEKSQMPERNLAVIEGFVSRIDVLDYDAAAATHT
GQIRAELARQGRPVGPFDQMIAGHARSRGLIIVTNNTREFERVGGLRIEDWS

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8542.58 Da        Isoelectric Point: 4.5358

>AT271587 WP_021541611.1 NZ_CP117592:61101-61328 [Escherichia albertii]
METTVFLSNRSQAVRLPKAVALPENVKRVEVIAVGRTRIITPAGETWDEWFDGNSVSADFMDNREQPSMQERESF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References