Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 879270..879921 Replicon chromosome
Accession NZ_CP117590
Organism Escherichia albertii strain BIA_36

Toxin (Protein)


Gene name cptA Uniprot ID B1EG01
Locus tag PS051_RS04265 Protein ID WP_000244763.1
Coordinates 879517..879921 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S1PPB1
Locus tag PS051_RS04260 Protein ID WP_000354046.1
Coordinates 879270..879536 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS051_RS04230 (874280) 874280..875173 + 894 WP_059221140.1 transporter -
PS051_RS04235 (875220) 875220..876653 - 1434 WP_273781680.1 6-phospho-beta-glucosidase BglA -
PS051_RS04240 (876698) 876698..877009 + 312 WP_001182957.1 N(4)-acetylcytidine aminohydrolase -
PS051_RS04245 (877177) 877177..877836 + 660 WP_000250281.1 hemolysin III family protein -
PS051_RS04250 (878038) 878038..879018 - 981 WP_273781681.1 tRNA-modifying protein YgfZ -
PS051_RS04255 (879050) 879050..879280 + 231 WP_000181267.1 hypothetical protein -
PS051_RS04260 (879270) 879270..879536 + 267 WP_000354046.1 FAD assembly factor SdhE Antitoxin
PS051_RS04265 (879517) 879517..879921 + 405 WP_000244763.1 protein YgfX Toxin
PS051_RS04270 (879955) 879955..880476 - 522 WP_059221135.1 flavodoxin FldB -
PS051_RS04275 (880588) 880588..881484 + 897 WP_273781682.1 site-specific tyrosine recombinase XerD -
PS051_RS04280 (881509) 881509..882219 + 711 WP_000748106.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PS051_RS04285 (882225) 882225..883958 + 1734 WP_273781683.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15888.81 Da        Isoelectric Point: 11.1732

>T271565 WP_000244763.1 NZ_CP117590:879517-879921 [Escherichia albertii]
VVLWQSDLRVSWRAQWLSLLIHGLVAAAILLMPWPLSYTPLWMVLLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQ
EWSIVRAPWMIKTGMMLRLLSDSGKRQHLWLAADSMDEAEWRDLRRILLQQEIQ

Download         Length: 405 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10547.12 Da        Isoelectric Point: 5.1599

>AT271565 WP_000354046.1 NZ_CP117590:879270-879536 [Escherichia albertii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S6P9B3

Antitoxin

Source ID Structure
PDB 6B58
PDB 1X6I
PDB 1X6J
PDB 6C12
AlphaFold DB A0A7U9QD57

References