Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 290947..291747 Replicon chromosome
Accession NZ_CP117590
Organism Escherichia albertii strain BIA_36

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag PS051_RS01335 Protein ID WP_059220924.1
Coordinates 291220..291747 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID B1EHP0
Locus tag PS051_RS01330 Protein ID WP_001277106.1
Coordinates 290947..291213 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS051_RS01310 (286603) 286603..287271 + 669 WP_000617720.1 cell division ATP-binding protein FtsE -
PS051_RS01315 (287264) 287264..288322 + 1059 WP_001042000.1 permease-like cell division protein FtsX -
PS051_RS01320 (288567) 288567..289421 + 855 WP_000130217.1 RNA polymerase sigma factor RpoH -
PS051_RS01325 (289694) 289694..290797 + 1104 WP_010319184.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS051_RS01330 (290947) 290947..291213 + 267 WP_001277106.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS051_RS01335 (291220) 291220..291747 + 528 WP_059220924.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS051_RS01340 (291744) 291744..292127 - 384 WP_273781558.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS051_RS01345 (292551) 292551..293660 + 1110 WP_273781559.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS051_RS01350 (293708) 293708..294634 + 927 WP_273781560.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS051_RS01355 (294631) 294631..295908 + 1278 WP_273781561.1 branched chain amino acid ABC transporter permease LivM -
PS051_RS01360 (295905) 295905..296672 + 768 WP_273781562.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19490.38 Da        Isoelectric Point: 6.6303

>T271564 WP_059220924.1 NZ_CP117590:291220-291747 [Escherichia albertii]
MDDLTIEILTDDADYDLQRLDCGEEALNLFLTTHLVRQHRNKILRAYILCSNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVCSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9942.37 Da        Isoelectric Point: 10.0863

>AT271564 WP_001277106.1 NZ_CP117590:290947-291213 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQHRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z8E004

References