Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 693173..694008 Replicon chromosome
Accession NZ_CP117580
Organism Escherichia albertii strain BIA_47

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag PS044_RS03400 Protein ID WP_001565141.1
Coordinates 693631..694008 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag PS044_RS03395 Protein ID WP_001565140.1
Coordinates 693173..693541 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS044_RS03375 (690921) 690921..691739 + 819 WP_021536653.1 DUF932 domain-containing protein -
PS044_RS03380 (691831) 691831..692316 + 486 WP_001565139.1 antirestriction protein -
PS044_RS03385 (692332) 692332..692808 + 477 WP_001186725.1 RadC family protein -
PS044_RS03390 (692877) 692877..693098 + 222 WP_000692303.1 DUF987 domain-containing protein -
PS044_RS03395 (693173) 693173..693541 + 369 WP_001565140.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PS044_RS03400 (693631) 693631..694008 + 378 WP_001565141.1 TA system toxin CbtA family protein Toxin
PS044_RS03405 (694005) 694005..694493 + 489 WP_001565142.1 DUF5983 family protein -
PS044_RS03410 (694505) 694505..694702 + 198 WP_000839256.1 DUF957 domain-containing protein -
PS044_RS03415 (694787) 694787..695632 + 846 WP_273808229.1 DUF4942 domain-containing protein -
PS044_RS03425 (695933) 695933..696439 + 507 WP_000245810.1 G/U mismatch-specific DNA glycosylase -
PS044_RS03430 (696519) 696519..698360 - 1842 WP_000437385.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(19-117)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14246.27 Da        Isoelectric Point: 7.2920

>T271496 WP_001565141.1 NZ_CP117580:693631-694008 [Escherichia albertii]
MKTLPDTHVREASRCPSPVTIWQTLLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SICPRSQLINSIDILRARRATGLMTRDNYRMVNNITQGKHPEAQQ

Download         Length: 378 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13604.41 Da        Isoelectric Point: 6.7389

>AT271496 WP_001565140.1 NZ_CP117580:693173-693541 [Escherichia albertii]
VSDTLPGTTHPDDNHDRLWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGRFSNADAYHLDQAFALLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCEADTLGSCGYVYLAVYPTPETKK

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References