Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type V Classification (family/domain) ghoTS/ghoT-GhoS
Location 3693286..3693783 Replicon chromosome
Accession NZ_CP117575
Organism Escherichia albertii strain BIA_5

Toxin (Protein)


Gene name ghoT Uniprot ID -
Locus tag PS037_RS17885 Protein ID WP_098402396.1
Coordinates 3693610..3693783 (+) Length 58 a.a.

Antitoxin (Protein)


Gene name ghoS Uniprot ID -
Locus tag PS037_RS17880 Protein ID WP_098402399.1
Coordinates 3693286..3693582 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS037_RS17865 (3688591) 3688591..3688890 + 300 WP_249922798.1 helix-turn-helix transcriptional regulator -
PS037_RS17870 (3689892) 3689892..3691724 - 1833 Protein_3488 hemagglutinin repeat-containing protein -
PS037_RS17880 (3693286) 3693286..3693582 + 297 WP_098402399.1 type V toxin-antitoxin system endoribonuclease antitoxin GhoS Antitoxin
PS037_RS17885 (3693610) 3693610..3693783 + 174 WP_098402396.1 type V toxin-antitoxin system toxin GhoT Toxin
PS037_RS17890 (3693902) 3693902..3695419 - 1518 WP_273771100.1 lysine--tRNA ligase -
PS037_RS17895 (3695749) 3695749..3697896 - 2148 WP_273821259.1 lysine decarboxylase CadA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - nleB1 / nleE / vat / vat 3693286..3728768 35482


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin GhoT/OrtT

(4-57)

Antitoxin

Endoribonuclease antitoxin GhoS

(5-94)


Sequences

Toxin        


Download         Length: 58 a.a.        Molecular weight: 6537.97 Da        Isoelectric Point: 10.2288

>T271487 WP_098402396.1 NZ_CP117575:3693610-3693783 [Escherichia albertii]
IALFSKILNFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITWPMSLPVALLFSLF

Download         Length: 174 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11564.29 Da        Isoelectric Point: 4.7106

>AT271487 WP_098402399.1 NZ_CP117575:3693286-3693582 [Escherichia albertii]
MKYKNKFNTYVVSFDYPSSYSSVFLRLRSLMCDMNFSSVVADEYVIPRQLNENSLAITTSLSTSKIEDLIRLKCLDLPDI
DFDLNIMIVDDYFRQFYK

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References