Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 2634956..2635756 Replicon chromosome
Accession NZ_CP117575
Organism Escherichia albertii strain BIA_5

Toxin (Protein)


Gene name ataT Uniprot ID A0A8H9C5V7
Locus tag PS037_RS12835 Protein ID WP_000342455.1
Coordinates 2634956..2635483 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A8H9C3F4
Locus tag PS037_RS12840 Protein ID WP_001277105.1
Coordinates 2635490..2635756 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS037_RS12810 (2630031) 2630031..2630798 - 768 WP_000082101.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -
PS037_RS12815 (2630795) 2630795..2632072 - 1278 WP_273821083.1 branched chain amino acid ABC transporter permease LivM -
PS037_RS12820 (2632069) 2632069..2632995 - 927 WP_001295111.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS037_RS12825 (2633043) 2633043..2634152 - 1110 WP_273821084.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS037_RS12830 (2634576) 2634576..2634959 + 384 WP_000778774.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS037_RS12835 (2634956) 2634956..2635483 - 528 WP_000342455.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS037_RS12840 (2635490) 2635490..2635756 - 267 WP_001277105.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS037_RS12845 (2635906) 2635906..2637009 - 1104 WP_273821085.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS037_RS12850 (2637532) 2637532..2637933 + 402 WP_001071334.1 PTS sugar transporter subunit IIA -
PS037_RS12855 (2637940) 2637940..2638425 + 486 WP_000029259.1 PTS sugar transporter subunit IIB -
PS037_RS12860 (2638442) 2638442..2639188 + 747 WP_000151888.1 PTS sugar transporter subunit IIC -
PS037_RS12865 (2639181) 2639181..2640035 + 855 WP_000370583.1 PTS system mannose/fructose/sorbose family transporter subunit IID -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-150)

Antitoxin

Vibrio phage ICP1, Orf50

(2-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19607.47 Da        Isoelectric Point: 6.6343

>T271481 WP_000342455.1 NZ_CP117575:c2635483-2634956 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCSNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9935.40 Da        Isoelectric Point: 9.2494

>AT271481 WP_001277105.1 NZ_CP117575:c2635756-2635490 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNCASQRAAEVIEQNRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References