Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 149274..149796 Replicon plasmid pEA50_1
Accession NZ_CP117571
Organism Escherichia albertii strain BIA_50

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PS035_RS23595 Protein ID WP_065106543.1
Coordinates 149515..149796 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PS035_RS23590 Protein ID WP_273818005.1
Coordinates 149274..149525 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS035_RS23575 (145629) 145629..145724 + 96 WP_000609147.1 DinQ-like type I toxin DqlB -
PS035_RS23580 (145941) 145941..147103 + 1163 WP_273818003.1 IS3 family transposase -
PS035_RS23585 (147301) 147301..148137 - 837 WP_273818004.1 replication initiation protein -
PS035_RS23590 (149274) 149274..149525 + 252 WP_273818005.1 plasmid stabilization protein Antitoxin
PS035_RS23595 (149515) 149515..149796 + 282 WP_065106543.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PS035_RS23600 (150175) 150175..151352 - 1178 Protein_164 IS91 family transposase -
PS035_RS23605 (151352) 151352..151717 - 366 WP_273818006.1 hypothetical protein -
PS035_RS23610 (151879) 151879..152355 + 477 WP_273818007.1 CesD/SycD/LcrH family type III secretion system chaperone -
PS035_RS23615 (152380) 152380..153078 + 699 WP_273818008.1 hypothetical protein -
PS035_RS23620 (153509) 153509..153943 + 435 Protein_168 transposase -
PS035_RS23625 (153982) 153982..154077 - 96 Protein_169 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid sitABCD vat / iutA / iucD / iucC / iucB / iucA / espK / paa / vat 1..165614 165614
- inside IScluster/Tn - - 139774..164869 25095


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11021.83 Da        Isoelectric Point: 10.5938

>T271466 WP_065106543.1 NZ_CP117571:149515-149796 [Escherichia albertii]
MTYELAFDRRALKEWQKLGHTIREQFKKKLSERLENPRVPAARLHGHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGR
RESSEVYQIADLR

Download         Length: 282 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9109.36 Da        Isoelectric Point: 4.2558

>AT271466 WP_273818005.1 NZ_CP117571:149274-149525 [Escherichia albertii]
MSYQILTTTAASITDLKKNPMGTVAEGEGGAVAILNRNEPAFYCVPPKLYAYYRELAEDAELNAVADERMKNPEIVKVSL
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References