Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1877402..1877992 Replicon chromosome
Accession NZ_CP117570
Organism Escherichia albertii strain BIA_50

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PS035_RS08890 Protein ID WP_059225520.1
Coordinates 1877660..1877992 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PS035_RS08885 Protein ID WP_059225519.1
Coordinates 1877402..1877659 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS035_RS08875 (1876382) 1876382..1876852 + 471 WP_059225518.1 hypothetical protein -
PS035_RS08880 (1876849) 1876849..1877054 + 206 Protein_1734 helix-turn-helix transcriptional regulator -
PS035_RS08885 (1877402) 1877402..1877659 + 258 WP_059225519.1 hypothetical protein Antitoxin
PS035_RS08890 (1877660) 1877660..1877992 + 333 WP_059225520.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PS035_RS08895 (1878105) 1878105..1878482 + 378 WP_161537949.1 hypothetical protein -
PS035_RS08900 (1878800) 1878800..1879684 + 885 WP_059225521.1 integrase domain-containing protein -
PS035_RS08905 (1879780) 1879780..1880067 - 288 WP_059225522.1 hypothetical protein -
PS035_RS08910 (1881026) 1881026..1882288 - 1263 WP_059225524.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(4-85)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11777.59 Da        Isoelectric Point: 8.0291

>T271450 WP_059225520.1 NZ_CP117570:1877660-1877992 [Escherichia albertii]
MDRGEIWLVSLDPIAGHEQSGKRPVLIVSPASFNEVTRLPVIVPVTSGGQFARSAGFAVSLEGAGTKTTGIIRCDQPRTI
DMGARNGKRLERIPDGIINEVLARLETILA

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9314.80 Da        Isoelectric Point: 4.4488

>AT271450 WP_059225519.1 NZ_CP117570:1877402-1877659 [Escherichia albertii]
MYTTRLKKVGGSVMLAVPPAVLKTLALLPDSEVGVTIDNGCLIIEPQKRPRYSLAELLAQCDPHEEISDEEREWIDAPAA
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References