Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 296803..297603 Replicon chromosome
Accession NZ_CP117570
Organism Escherichia albertii strain BIA_50

Toxin (Protein)


Gene name ataT Uniprot ID A0A8H9C5V7
Locus tag PS035_RS01375 Protein ID WP_000342455.1
Coordinates 297076..297603 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PS035_RS01370 Protein ID WP_098401847.1
Coordinates 296803..297069 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS035_RS01345 (292524) 292524..293378 - 855 Protein_265 PTS system mannose/fructose/sorbose family transporter subunit IID -
PS035_RS01350 (293371) 293371..294117 - 747 WP_000151888.1 PTS sugar transporter subunit IIC -
PS035_RS01355 (294134) 294134..294619 - 486 WP_000029259.1 PTS sugar transporter subunit IIB -
PS035_RS01360 (294626) 294626..295027 - 402 WP_001071334.1 PTS sugar transporter subunit IIA -
PS035_RS01365 (295550) 295550..296653 + 1104 WP_149449696.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS035_RS01370 (296803) 296803..297069 + 267 WP_098401847.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS035_RS01375 (297076) 297076..297603 + 528 WP_000342455.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS035_RS01380 (297600) 297600..297983 - 384 WP_000778774.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS035_RS01385 (298393) 298393..299502 + 1110 WP_000827693.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS035_RS01390 (299550) 299550..300476 + 927 WP_001295097.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS035_RS01395 (300473) 300473..301750 + 1278 WP_044709902.1 branched chain amino acid ABC transporter permease LivM -
PS035_RS01400 (301747) 301747..302514 + 768 WP_273817600.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19607.47 Da        Isoelectric Point: 6.6343

>T271448 WP_000342455.1 NZ_CP117570:297076-297603 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCSNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9919.34 Da        Isoelectric Point: 10.0862

>AT271448 WP_098401847.1 NZ_CP117570:296803-297069 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQNRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References