Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 40550..41085 Replicon plasmid pEA7_1
Accession NZ_CP117563
Organism Escherichia albertii strain BIA_7

Toxin (Protein)


Gene name relE Uniprot ID A0A8H9KAX0
Locus tag PS049_RS24790 Protein ID WP_000222759.1
Coordinates 40550..40837 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8H9KB11
Locus tag PS049_RS24795 Protein ID WP_001132891.1
Coordinates 40834..41085 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS049_RS24765 (36066) 36066..37658 - 1593 WP_006703274.1 IS66 family transposase -
PS049_RS24770 (37689) 37689..38039 - 351 WP_000624677.1 IS66 family insertion sequence element accessory protein TnpB -
PS049_RS24775 (38036) 38036..38455 - 420 WP_000422694.1 transposase -
PS049_RS24780 (38931) 38931..39110 + 180 Protein_33 transposase domain-containing protein -
PS049_RS24785 (39457) 39457..40414 - 958 Protein_34 RNA-guided endonuclease TnpB family protein -
PS049_RS24790 (40550) 40550..40837 - 288 WP_000222759.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PS049_RS24795 (40834) 40834..41085 - 252 WP_001132891.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PS049_RS24800 (41607) 41607..42578 - 972 WP_062862136.1 ParB/RepB/Spo0J family plasmid partition protein -
PS049_RS24805 (42578) 42578..43744 - 1167 WP_062860116.1 plasmid-partitioning protein SopA -
PS049_RS24810 (44168) 44168..44948 - 781 Protein_39 IS21-like element helper ATPase IstB -
PS049_RS24815 (44945) 44945..45755 - 811 Protein_40 DDE-type integrase/transposase/recombinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - efa1 1..177310 177310
- inside IScluster/Tn - - 36066..57092 21026


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11176.23 Da        Isoelectric Point: 10.5832

>T271415 WP_000222759.1 NZ_CP117563:c40837-40550 [Escherichia albertii]
MTYTVKFRDDALKEWLKLDKSIQQQFAKKLKKCSENPHIPSAKLRELKNCYKIKLRASGFRLVYQVIDDMLIIAVVAVGK
RERSNVYNLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9181.39 Da        Isoelectric Point: 4.0780

>AT271415 WP_001132891.1 NZ_CP117563:c41085-40834 [Escherichia albertii]
MPNIILSDTSASVSELKKNPMATVGAGDGYPVAILNRNQPAFYCVPAELYERMLDALDDQELVKLVTERSNQPLHDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References