Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 1491873..1492673 Replicon chromosome
Accession NZ_CP117562
Organism Escherichia albertii strain BIA_7

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag PS049_RS07140 Protein ID WP_273820179.1
Coordinates 1492146..1492673 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PS049_RS07135 Protein ID WP_001277104.1
Coordinates 1491873..1492139 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS049_RS07110 (1487594) 1487594..1488448 - 855 WP_000370584.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
PS049_RS07115 (1488441) 1488441..1489187 - 747 WP_000151888.1 PTS sugar transporter subunit IIC -
PS049_RS07120 (1489204) 1489204..1489689 - 486 WP_000029259.1 PTS sugar transporter subunit IIB -
PS049_RS07125 (1489696) 1489696..1490097 - 402 WP_001071334.1 PTS sugar transporter subunit IIA -
PS049_RS07130 (1490620) 1490620..1491723 + 1104 WP_010319184.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS049_RS07135 (1491873) 1491873..1492139 + 267 WP_001277104.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS049_RS07140 (1492146) 1492146..1492673 + 528 WP_273820179.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS049_RS07145 (1492670) 1492670..1493053 - 384 WP_059270572.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS049_RS07150 (1493477) 1493477..1494586 + 1110 WP_000827693.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS049_RS07155 (1494634) 1494634..1495560 + 927 WP_001295097.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS049_RS07160 (1495557) 1495557..1496834 + 1278 WP_059218996.1 branched chain amino acid ABC transporter permease LivM -
PS049_RS07165 (1496831) 1496831..1497598 + 768 WP_059218997.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19554.42 Da        Isoelectric Point: 6.3254

>T271398 WP_273820179.1 NZ_CP117562:1492146-1492673 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCSNTPECQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9958.44 Da        Isoelectric Point: 9.2519

>AT271398 WP_001277104.1 NZ_CP117562:1491873-1492139 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNCASQRAAEVIEQHRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References