Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 31633..32192 Replicon plasmid pEA8_2
Accession NZ_CP117560
Organism Escherichia albertii strain BIA_8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PS052_RS23950 Protein ID WP_024222961.1
Coordinates 31917..32192 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PS052_RS23945 Protein ID WP_053264228.1
Coordinates 31633..31917 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS052_RS23925 (27079) 27079..27825 - 747 Protein_25 esterase-like activity of phytase family protein -
PS052_RS23930 (27961) 27961..28092 - 132 Protein_26 IS3 family transposase -
PS052_RS23935 (28245) 28245..29018 - 774 WP_024222958.1 hypothetical protein -
PS052_RS23940 (29746) 29746..30952 + 1207 Protein_28 IS3 family transposase -
PS052_RS23945 (31633) 31633..31917 + 285 WP_053264228.1 ribbon-helix-helix domain-containing protein Antitoxin
PS052_RS23950 (31917) 31917..32192 + 276 WP_024222961.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PS052_RS23955 (32285) 32285..32488 + 204 Protein_31 hypothetical protein -
PS052_RS23960 (32977) 32977..33189 - 213 WP_143364308.1 hypothetical protein -
PS052_RS23965 (33792) 33792..33986 + 195 WP_137495149.1 hypothetical protein -
PS052_RS23975 (35187) 35187..35951 + 765 WP_000340226.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..91469 91469
- inside IScluster/Tn - - 18455..34831 16376


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(14-51)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10735.46 Da        Isoelectric Point: 10.1792

>T271384 WP_024222961.1 NZ_CP117560:31917-32192 [Escherichia albertii]
MELKWTSKALSDLARLYDFLVLASKPAAARTVQSLTQAPVILLTHPRMGEQLFQFDPREVRRIFAGEYEIRYELNGKTIY
VLRLWHTRENR

Download         Length: 276 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10442.83 Da        Isoelectric Point: 5.6558

>AT271384 WP_053264228.1 NZ_CP117560:31633-31917 [Escherichia albertii]
MQMKNNTAQATKVITAHVPLPMADKVDQVAARLERSRGWVIKQALSAWLAQEEERNRLTLEALDDVTSGQVIDHQAVQAW
ADSLSTDNPLPVPR

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References