Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 280137..280937 Replicon chromosome
Accession NZ_CP117558
Organism Escherichia albertii strain BIA_8

Toxin (Protein)


Gene name ataT Uniprot ID B1EHN9
Locus tag PS052_RS01340 Protein ID WP_000342453.1
Coordinates 280410..280937 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PS052_RS01335 Protein ID WP_098401847.1
Coordinates 280137..280403 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS052_RS01310 (275858) 275858..276712 - 855 WP_105227881.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
PS052_RS01315 (276705) 276705..277451 - 747 WP_000151888.1 PTS sugar transporter subunit IIC -
PS052_RS01320 (277468) 277468..277953 - 486 WP_000029259.1 PTS sugar transporter subunit IIB -
PS052_RS01325 (277960) 277960..278361 - 402 WP_103054017.1 PTS sugar transporter subunit IIA -
PS052_RS01330 (278884) 278884..279987 + 1104 Protein_263 branched chain amino acid ABC transporter substrate-binding protein LivJ -
PS052_RS01335 (280137) 280137..280403 + 267 WP_098401847.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
PS052_RS01340 (280410) 280410..280937 + 528 WP_000342453.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
PS052_RS01345 (280934) 280934..281317 - 384 WP_103054016.1 aspartate 1-decarboxylase autocleavage activator PanM -
PS052_RS01350 (281741) 281741..282850 + 1110 WP_103054015.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
PS052_RS01355 (282898) 282898..283824 + 927 WP_001295111.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
PS052_RS01360 (283821) 283821..285098 + 1278 WP_273765174.1 branched chain amino acid ABC transporter permease LivM -
PS052_RS01365 (285095) 285095..285862 + 768 WP_000082101.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(88-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19676.58 Da        Isoelectric Point: 6.9585

>T271363 WP_000342453.1 NZ_CP117558:280410-280937 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCRNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9919.34 Da        Isoelectric Point: 10.0862

>AT271363 WP_098401847.1 NZ_CP117558:280137-280403 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQNRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References