Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4526165..4526760 Replicon chromosome
Accession NZ_CP117556
Organism Escherichia albertii strain BIA_89-5

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag PS032_RS22705 Protein ID WP_059255551.1
Coordinates 4526165..4526515 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag PS032_RS22710 Protein ID WP_059255553.1
Coordinates 4526509..4526760 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS032_RS22685 (4521770) 4521770..4522738 + 969 WP_137650502.1 PfkB family carbohydrate kinase -
PS032_RS22690 (4522791) 4522791..4524134 + 1344 WP_273806757.1 sugar porter family MFS transporter -
PS032_RS22695 (4524220) 4524220..4524720 + 501 WP_059255546.1 D-ribose pyranase -
PS032_RS22700 (4524733) 4524733..4526112 + 1380 WP_137650500.1 sugar porter family MFS transporter -
PS032_RS22705 (4526165) 4526165..4526515 - 351 WP_059255551.1 type II toxin-antitoxin system ChpB family toxin Toxin
PS032_RS22710 (4526509) 4526509..4526760 - 252 WP_059255553.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PS032_RS22715 (4526969) 4526969..4527313 - 345 WP_001219163.1 gamma-glutamylcyclotransferase -
PS032_RS22720 (4527316) 4527316..4531095 - 3780 WP_137650499.1 autotransporter assembly complex protein TamB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12631.65 Da        Isoelectric Point: 5.1420

>T271357 WP_059255551.1 NZ_CP117556:c4526515-4526165 [Escherichia albertii]
MVKRSEFERGDIMLVGFDPASGHEQRGAGRPVLVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLRCEEGDVCGVVVV
NQVRMMDLNARQAKRIGLACDEVVEEVLLRLQAVVE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9237.69 Da        Isoelectric Point: 4.9431

>AT271357 WP_059255553.1 NZ_CP117556:c4526760-4526509 [Escherichia albertii]
MRITIKKWGNSAGMVIPNIVMKGLKLQPGQSLEAQVRNNQLILTPVSKRYSLDELLAQCDMNAPELSEQDVWGTLSPAGD
EIW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References