Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | paaR-paaA-parE/- |
Location | 2362877..2363349 | Replicon | chromosome |
Accession | NZ_CP117556 | ||
Organism | Escherichia albertii strain BIA_89-5 |
Toxin (Protein)
Gene name | parE_1 | Uniprot ID | - |
Locus tag | PS032_RS11770 | Protein ID | WP_042898926.1 |
Coordinates | 2362877..2363158 (-) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | paaA | Uniprot ID | - |
Locus tag | PS032_RS11775 | Protein ID | WP_001090452.1 |
Coordinates | 2363158..2363349 (-) | Length | 64 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PS032_RS11745 (2360185) | 2360185..2360460 | - | 276 | WP_044805262.1 | hypothetical protein | - |
PS032_RS11750 (2360596) | 2360596..2360817 | - | 222 | WP_062898151.1 | cell division protein FtsZ | - |
PS032_RS11755 (2360864) | 2360864..2361715 | - | 852 | WP_137650430.1 | Rha family phage regulatory protein | - |
PS032_RS11760 (2362221) | 2362221..2362415 | + | 195 | WP_074464194.1 | hypothetical protein | - |
PS032_RS11765 (2362381) | 2362381..2362599 | - | 219 | WP_000232638.1 | hypothetical protein | - |
PS032_RS11770 (2362877) | 2362877..2363158 | - | 282 | WP_042898926.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
PS032_RS11775 (2363158) | 2363158..2363349 | - | 192 | WP_001090452.1 | hypothetical protein | Antitoxin |
PS032_RS11780 (2363380) | 2363380..2363778 | - | 399 | WP_000209118.1 | helix-turn-helix domain-containing protein | - |
PS032_RS11785 (2363895) | 2363895..2364161 | + | 267 | WP_074404412.1 | YdaS family helix-turn-helix protein | - |
PS032_RS11790 (2364158) | 2364158..2364583 | + | 426 | WP_149452502.1 | toxin YdaT family protein | - |
PS032_RS11795 (2364655) | 2364655..2365695 | + | 1041 | WP_137650431.1 | DnaT-like ssDNA-binding domain-containing protein | - |
PS032_RS11800 (2365688) | 2365688..2366149 | + | 462 | WP_262409891.1 | replication protein P | - |
PS032_RS11805 (2366182) | 2366182..2366924 | + | 743 | Protein_2312 | DUF1627 domain-containing protein | - |
PS032_RS11810 (2366911) | 2366911..2367117 | + | 207 | WP_053893343.1 | hypothetical protein | - |
PS032_RS11815 (2367114) | 2367114..2367368 | + | 255 | WP_001294161.1 | hypothetical protein | - |
PS032_RS11820 (2367361) | 2367361..2367492 | + | 132 | Protein_2315 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2354664..2398461 | 43797 | |
- | flank | IS/Tn | - | - | 2367498..2368538 | 1040 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10719.56 Da Isoelectric Point: 10.1409
>T271344 WP_042898926.1 NZ_CP117556:c2363158-2362877 [Escherichia albertii]
MLPILWLPSARDDLRQIVAYIAKENLHAARRLKIRIETCVLALSEHPYLYPSSDRVSGLREIVAHPNYIILYRVATSSIE
IVSVAHARRQFPR
MLPILWLPSARDDLRQIVAYIAKENLHAARRLKIRIETCVLALSEHPYLYPSSDRVSGLREIVAHPNYIILYRVATSSIE
IVSVAHARRQFPR
Download Length: 282 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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