Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2870626..2871079 Replicon chromosome
Accession NZ_CP117554
Organism Erwinia amylovora strain 99east-3-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PTC76_RS13170 Protein ID WP_013035888.1
Coordinates 2870626..2870862 (-) Length 79 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D4HZA2
Locus tag PTC76_RS13175 Protein ID WP_004159527.1
Coordinates 2870852..2871079 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTC76_RS13150 (PTC76_13150) 2866141..2867019 - 879 WP_004159509.1 Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD -
PTC76_RS13155 (PTC76_13155) 2867034..2867828 - 795 WP_004159512.1 Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC -
PTC76_RS13160 (PTC76_13160) 2867877..2870093 - 2217 Protein_2554 ferrichrome porin FhuA -
PTC76_RS13165 (PTC76_13165) 2870421..2870639 + 219 WP_004159522.1 hypothetical protein -
PTC76_RS13170 (PTC76_13170) 2870626..2870862 - 237 WP_013035888.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PTC76_RS13175 (PTC76_13175) 2870852..2871079 - 228 WP_004159527.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PTC76_RS13180 (PTC76_13180) 2871400..2871687 + 288 WP_264072243.1 type I toxin-antitoxin system SymE family toxin -
PTC76_RS13185 (PTC76_13185) 2871751..2872155 - 405 WP_013035886.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-78)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-75)


Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 9135.79 Da        Isoelectric Point: 9.0876

>T271327 WP_013035888.1 NZ_CP117554:c2870862-2870626 [Erwinia amylovora]
ISYELLFDPWALKEWKKLGATVREQFKKKLAEVLVNLQVESARLRDHPDCCKIKLKSSGYRLVYQVQDEQLVMLVISV

Download         Length: 237 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8435.90 Da        Isoelectric Point: 7.9766

>AT271327 WP_004159527.1 NZ_CP117554:c2871079-2870852 [Erwinia amylovora]
VRLDDKLKSKACAVLDELDVSPTEAVRLLFQYIAENERLPLKALTVSDEKDALLKTVRERLASLQKGIKVTLDKL

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A831A410

References