Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/PRK09907-MazE
Location 215652..216223 Replicon chromosome
Accession NZ_CP117526
Organism Fusobacterium nucleatum strain FNU

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PSR67_RS00995 Protein ID WP_273858556.1
Coordinates 215900..216223 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PSR67_RS00990 Protein ID WP_273858555.1
Coordinates 215652..215906 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR67_RS00990 (PSR67_00990) 215652..215906 + 255 WP_273858555.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PSR67_RS00995 (PSR67_00995) 215900..216223 + 324 WP_273858556.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PSR67_RS01000 (PSR67_01000) 216278..217264 - 987 WP_273858557.1 ABC transporter ATP-binding protein -
PSR67_RS01005 (PSR67_01005) 217245..218030 - 786 WP_273858558.1 ABC transporter ATP-binding protein -
PSR67_RS01010 (PSR67_01010) 218042..219622 - 1581 WP_273858559.1 ABC transporter substrate-binding protein -
PSR67_RS01015 (PSR67_01015) 219672..220502 - 831 WP_273858560.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-106)

Antitoxin

Antitoxin PemI-like

(4-81)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12411.50 Da        Isoelectric Point: 6.2368

>T271314 WP_273858556.1 NZ_CP117526:215900-216223 [Fusobacterium nucleatum]
VVKRGDIIIINFNPVKGHEQAGKRPALVISNEKFYKIFKLAVILPITNNTKDFPFHVLLDERTNIKGAILCEHLRTVDLE
ERKYDKIEEIPEDLLEEVLEKVSLIFQ

Download         Length: 324 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 10015.46 Da        Isoelectric Point: 4.9117

>AT271314 WP_273858555.1 NZ_CP117526:215652-215906 [Fusobacterium nucleatum]
MEVLRVQKWGNSQGIRLPKKILKDLGIDVNDKIEISLNDGEIILRKVKKYIDLDDLFKDYKGDYREDFAEFEFFGEAQGR
EFKW

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References