Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 144852..145369 Replicon chromosome
Accession NZ_CP117526
Organism Fusobacterium nucleatum strain FNU

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PSR67_RS00655 Protein ID WP_150152250.1
Coordinates 145112..145369 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PSR67_RS00650 Protein ID WP_150152248.1
Coordinates 144852..145109 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR67_RS00630 (PSR67_00630) 139978..142074 + 2097 WP_273858489.1 outer membrane protein assembly factor -
PSR67_RS00635 (PSR67_00635) 142115..142591 + 477 WP_150152242.1 OmpH family outer membrane protein -
PSR67_RS00640 (PSR67_00640) 142612..143610 + 999 WP_273858492.1 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase -
PSR67_RS00645 (PSR67_00645) 143659..144732 + 1074 WP_273858493.1 glycerophosphodiester phosphodiesterase -
PSR67_RS00650 (PSR67_00650) 144852..145109 + 258 WP_150152248.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PSR67_RS00655 (PSR67_00655) 145112..145369 + 258 WP_150152250.1 Txe/YoeB family addiction module toxin Toxin
PSR67_RS00660 (PSR67_00660) 145485..146561 + 1077 WP_273858496.1 DHH family phosphoesterase -
PSR67_RS00665 (PSR67_00665) 146667..147404 + 738 WP_273858498.1 tRNA pseudouridine(38-40) synthase TruA -
PSR67_RS00670 (PSR67_00670) 147562..148449 + 888 WP_273858499.1 POTRA domain-containing protein -
PSR67_RS00675 (PSR67_00675) 148427..148933 + 507 WP_273858500.1 DUF2247 family protein -
PSR67_RS00680 (PSR67_00680) 148963..149340 + 378 WP_273858502.1 hypothetical protein -
PSR67_RS00685 (PSR67_00685) 149581..150156 + 576 WP_273858504.1 aminoacyl-tRNA hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10227.82 Da        Isoelectric Point: 8.8798

>T271313 WP_150152250.1 NZ_CP117526:145112-145369 [Fusobacterium nucleatum]
MKIIWNDKAWEEYVEWQTIDRKIVKKINELIKDIQKNGNEGIGKPELLQHELSGYWSRRITEKHRLIYFITENQLVIIGC
SGHYK

Download         Length: 258 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10235.53 Da        Isoelectric Point: 4.8951

>AT271313 WP_150152248.1 NZ_CP117526:144852-145109 [Fusobacterium nucleatum]
MIATNYSEVRNNLKTYCDKATKDYETIIITRKNNENVVLMSEEKYNNLMENLYIMSNKDYYNELVRRKKEIEKGNYAEHD
LIEVD

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References