271311

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 227163..227677 Replicon chromosome
Accession NZ_CP117525
Organism Fusobacterium nucleatum strain FNV

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag PSR69_RS01155 Protein ID WP_273833615.1
Coordinates 227420..227677 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A806U1B6
Locus tag PSR69_RS01150 Protein ID WP_029598877.1
Coordinates 227163..227420 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR69_RS01130 (PSR69_01130) 222302..224395 + 2094 WP_032844046.1 outer membrane protein assembly factor -
PSR69_RS01135 (PSR69_01135) 224436..224909 + 474 WP_005892890.1 OmpH family outer membrane protein -
PSR69_RS01140 (PSR69_01140) 224932..225930 + 999 WP_023035775.1 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase -
PSR69_RS01145 (PSR69_01145) 225973..227043 + 1071 WP_273833614.1 glycerophosphodiester phosphodiesterase -
PSR69_RS01150 (PSR69_01150) 227163..227420 + 258 WP_029598877.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PSR69_RS01155 (PSR69_01155) 227420..227677 + 258 WP_273833615.1 Txe/YoeB family addiction module toxin Toxin
PSR69_RS01160 (PSR69_01160) 227793..228869 + 1077 WP_005911995.1 DHH family phosphoesterase -
PSR69_RS01165 (PSR69_01165) 229104..229841 + 738 WP_008796318.1 tRNA pseudouridine(38-40) synthase TruA -
PSR69_RS01170 (PSR69_01170) 229983..230558 + 576 WP_005911993.1 aminoacyl-tRNA hydrolase -
PSR69_RS01175 (PSR69_01175) 230632..231939 + 1308 WP_005911992.1 electron transport complex subunit RsxC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10133.62 Da        Isoelectric Point: 8.8765

>T271311 WP_273833615.1 NZ_CP117525:227420-227677 [Fusobacterium nucleatum]
MLLTWTDFAWEQYEELQEKDKRLVKKINTLIKDIKRNGNEGIGKPEPLQHELSGYWSRRIDDKNRLVYKISDSQIIIVAC
ANHYK

Download         Length: 258 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10154.44 Da        Isoelectric Point: 4.7022

>AT271311 WP_029598877.1 NZ_CP117525:227163-227420 [Fusobacterium nucleatum]
MIATNYSEVRNNLKTYCDKATKDYETIIITRKNNENVVLMSEEEYNNLMENLYIRSNLKYYQRLVESIKEVEKGNVKEHD
LVEVD

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A806U1B6

References