Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 851870..852666 Replicon chromosome
Accession NZ_CP117518
Organism Photobacterium sp. GSS17

Toxin (Protein)


Gene name - Uniprot ID A0A0J1K069
Locus tag PGW97_RS20325 Protein ID WP_047885761.1
Coordinates 851870..852400 (-) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A0J1H842
Locus tag PGW97_RS20330 Protein ID WP_047885762.1
Coordinates 852397..852666 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGW97_RS20305 848365..849258 - 894 WP_273860577.1 alpha/beta hydrolase -
PGW97_RS20310 849389..850690 - 1302 WP_107193873.1 Y-family DNA polymerase -
PGW97_RS20315 850696..851079 - 384 WP_047886305.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
PGW97_RS20320 851366..851776 + 411 WP_047885760.1 SPOR domain-containing protein -
PGW97_RS20325 851870..852400 - 531 WP_047885761.1 GNAT family N-acetyltransferase Toxin
PGW97_RS20330 852397..852666 - 270 WP_047885762.1 DUF1778 domain-containing protein Antitoxin
PGW97_RS20335 852798..854249 - 1452 WP_084712588.1 MATE family efflux transporter -
PGW97_RS20340 854425..855402 + 978 WP_207103729.1 LysR family transcriptional regulator -
PGW97_RS20345 855446..856378 - 933 WP_273860578.1 FAD-binding protein -
PGW97_RS20350 856378..857127 - 750 WP_047885765.1 electron transfer flavoprotein subunit beta/FixA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(2-81)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19877.20 Da        Isoelectric Point: 9.6044

>T271310 WP_047885761.1 NZ_CP117518:c852400-851870 [Photobacterium sp. GSS17]
VSWSKTFVELDKHVHDRASFDCGEAELNTFIQTQASKHMQAGISRTMVLPASLPLLNQKWPICAFYSVAPSSIRRETLPV
SLAKKLPNYPIPVFLLAQLAVHREYHGHGLGKVSLIRALKYLWEVNAHMRAYAIVVDCLTPAAEAFYTKYGFQVLCDHNG
RTRMFIPMKTVGQLFS

Download         Length: 531 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9922.18 Da        Isoelectric Point: 4.3216

>AT271310 WP_047885762.1 NZ_CP117518:c852666-852397 [Photobacterium sp. GSS17]
MATARLDLRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIAQHESMTVQNDVFDRFMDACDKAEAPNQALRDAA
AFTEENGFK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1K069

Antitoxin

Source ID Structure
AlphaFold DB A0A0J1H842

References