Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1970458..1970603 Replicon chromosome
Accession NZ_CP117481
Organism Klebsiella pneumoniae strain DS-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1970494..1970596 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1970458..1970603 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PPH92_RS09680 1965588..1967648 + 2061 WP_004151449.1 oligopeptidase B -
PPH92_RS09685 1967652..1968311 - 660 WP_002911407.1 exodeoxyribonuclease X -
PPH92_RS09690 1968390..1968620 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PPH92_RS09695 1968733..1969107 + 375 WP_004151448.1 CopC domain-containing protein YobA -
PPH92_RS09700 1969111..1969980 + 870 WP_156731517.1 copper homeostasis membrane protein CopD -
PPH92_RS09705 1969997..1970335 + 339 WP_002911404.1 YebY family protein -
- 1970458..1970603 - 146 - - Antitoxin
- 1970494..1970596 + 103 - - Toxin
PPH92_RS09710 1970971..1971114 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
PPH92_RS09715 1971219..1972187 - 969 WP_004151446.1 VirK/YbjX family protein -
PPH92_RS09720 1972344..1972997 + 654 WP_156731516.1 protein-serine/threonine phosphatase -
PPH92_RS09725 1972994..1973185 - 192 WP_002911395.1 YebW family protein -
PPH92_RS09730 1973283..1973522 - 240 WP_002911393.1 YebV family protein -
PPH92_RS09735 1973638..1975071 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T271232 NZ_CP117481:1970494-1970596 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT271232 NZ_CP117481:c1970603-1970458 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References