Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 9923..10482 Replicon plasmid unnamed1
Accession NZ_CP117472
Organism Sphingobium sp. YC-XJ3

Toxin (Protein)


Gene name relE Uniprot ID T0H6G6
Locus tag PO876_RS25050 Protein ID WP_020819388.1
Coordinates 10189..10482 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID T0J1T8
Locus tag PO876_RS25045 Protein ID WP_020819389.1
Coordinates 9923..10192 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO876_RS25040 (PO876_25040) 6109..9558 + 3450 WP_020819391.1 YhaN family protein -
PO876_RS25045 (PO876_25045) 9923..10192 + 270 WP_020819389.1 ribbon-helix-helix domain-containing protein Antitoxin
PO876_RS25050 (PO876_25050) 10189..10482 + 294 WP_020819388.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PO876_RS25055 (PO876_25055) 10522..10965 - 444 WP_020819387.1 hypothetical protein -
PO876_RS25060 (PO876_25060) 10962..11810 - 849 WP_066521295.1 toprim domain-containing protein -
PO876_RS25065 (PO876_25065) 11982..12164 + 183 WP_020819384.1 hypothetical protein -
PO876_RS25070 (PO876_25070) 12372..13568 + 1197 WP_015460581.1 AAA family ATPase -
PO876_RS25075 (PO876_25075) 13565..14635 + 1071 WP_025160828.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..284951 284951


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11354.99 Da        Isoelectric Point: 7.3579

>T271225 WP_020819388.1 NZ_CP117472:10189-10482 [Sphingobium sp. YC-XJ3]
MKIQWTSKASSDLVRLHEHLGPVAPEAAARVVQQLAHAPDRLIDYPRIGEKLEAYEPREVRRIIVGNYEMRYEIAAGTIF
ILRLWHCRENRNFESEQ

Download         Length: 294 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9829.20 Da        Isoelectric Point: 5.1312

>AT271225 WP_020819389.1 NZ_CP117472:9923-10192 [Sphingobium sp. YC-XJ3]
MATETKVLTAHVPLGLAEKVEAMASRLERSRGWVVKQALAAWVDQEEERHRMTLEALEDVDAGRVIDHQAITAWADSLGT
DKPLPSPVK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T4HNW0

Antitoxin

Source ID Structure
AlphaFold DB A0A2T4HNW7

References