Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3513200..3513969 Replicon chromosome
Accession NZ_CP117471
Organism Sphingobium sp. YC-XJ3

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag PO876_RS17085 Protein ID WP_021688186.1
Coordinates 3513200..3513637 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag PO876_RS17090 Protein ID WP_021688187.1
Coordinates 3513724..3513969 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO876_RS17050 (PO876_17050) 3508247..3508726 - 480 WP_021688180.1 hypothetical protein -
PO876_RS17055 (PO876_17055) 3508732..3509487 - 756 WP_021688181.1 hypothetical protein -
PO876_RS17060 (PO876_17060) 3509531..3509992 - 462 WP_021688182.1 hypothetical protein -
PO876_RS17065 (PO876_17065) 3510004..3510651 - 648 WP_021688183.1 hypothetical protein -
PO876_RS17070 (PO876_17070) 3510725..3510865 - 141 WP_157034366.1 hypothetical protein -
PO876_RS17075 (PO876_17075) 3510875..3511978 - 1104 WP_223308141.1 hypothetical protein -
PO876_RS17080 (PO876_17080) 3512523..3512864 - 342 WP_021688185.1 sigma factor-like helix-turn-helix DNA-binding protein -
PO876_RS17085 (PO876_17085) 3513200..3513637 - 438 WP_021688186.1 hypothetical protein Toxin
PO876_RS17090 (PO876_17090) 3513724..3513969 - 246 WP_021688187.1 DUF1778 domain-containing protein Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3493332..3591831 98499


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(2-77)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15740.10 Da        Isoelectric Point: 9.9035

>T271224 WP_021688186.1 NZ_CP117471:c3513637-3513200 [Sphingobium sp. YC-XJ3]
MRRYARQSHELGGAKTFLAVDDTDNKTILGFYSIAPGSMDHADTPELARRGLARHEVPGFRLARLATDIRVQGNGLGGQL
LGAIGRRCIRVAAEVGGVMLIIDAKNERAAAWYASYGAITLHDKPLTLILPFATLERELRSAGQL

Download         Length: 438 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8832.28 Da        Isoelectric Point: 8.8557

>AT271224 WP_021688187.1 NZ_CP117471:c3513969-3513724 [Sphingobium sp. YC-XJ3]
MSLRIRPEQKALLARAAALRHTDLTTFVTGSALREAESVIEEAERTKLSERDSLLVLDLLENPPPANAKLRAAIAAMPKL
A

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References