Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 445133..445661 Replicon chromosome
Accession NZ_CP117471
Organism Sphingobium sp. YC-XJ3

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PO876_RS02050 Protein ID WP_274051983.1
Coordinates 445371..445661 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag PO876_RS02045 Protein ID WP_274051980.1
Coordinates 445133..445378 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO876_RS02030 (PO876_02030) 440180..441535 - 1356 WP_009823940.1 tyrosine-type recombinase/integrase -
PO876_RS02035 (PO876_02035) 441532..442764 - 1233 WP_007015824.1 site-specific integrase -
PO876_RS02040 (PO876_02040) 442922..445018 + 2097 WP_274051978.1 strawberry notch C-terminal domain-containing protein -
PO876_RS02045 (PO876_02045) 445133..445378 + 246 WP_274051980.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
PO876_RS02050 (PO876_02050) 445371..445661 + 291 WP_274051983.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PO876_RS02055 (PO876_02055) 445844..447523 + 1680 WP_274051985.1 ATP-binding protein -
PO876_RS02060 (PO876_02060) 447630..448820 + 1191 WP_274051987.1 DUF932 domain-containing protein -
PO876_RS02065 (PO876_02065) 448875..449456 + 582 WP_274051988.1 hypothetical protein -
PO876_RS02070 (PO876_02070) 449518..449820 + 303 WP_274051989.1 hypothetical protein -
PO876_RS02075 (PO876_02075) 449842..450537 + 696 WP_274051991.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 368513..485731 117218


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(7-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11175.81 Da        Isoelectric Point: 9.0764

>T271219 WP_274051983.1 NZ_CP117471:445371-445661 [Sphingobium sp. YC-XJ3]
MAEFRLSPRAQRDIDGIFDYTVKHWGLPQALRYMDLIEAACTSLADAPQQAQDCSVIRPGYRRRSVELHSIYFRQTSYGI
AVIRILHQRMDPSRHI

Download         Length: 291 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9304.34 Da        Isoelectric Point: 5.1373

>AT271219 WP_274051980.1 NZ_CP117471:445133-445378 [Sphingobium sp. YC-XJ3]
MAAVRKTITLTEQQDAWIASQIAAGHYTNDSEAIRDLIRREQERSFEIETIRQALIEGEQSGEPERFDFAAFKQRKIAQH
G

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References