271211

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii(toxin)
Location 88875..90650 Replicon plasmid unnamed1
Accession NZ_CP117405
Organism Lactococcus lactis strain LB7

Toxin (Protein)


Gene name abiEi Uniprot ID -
Locus tag IL310_RS00500 Protein ID WP_201249023.1
Coordinates 88875..89759 (-) Length 295 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID -
Locus tag IL310_RS00505 Protein ID WP_201249024.1
Coordinates 89781..90650 (-) Length 290 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IL310_RS00460 (IL310_00465) 84420..84662 - 243 WP_058211492.1 GlsB/YeaQ/YmgE family stress response membrane protein -
IL310_RS00465 (IL310_00470) 84900..85346 + 447 WP_201249139.1 DUF3290 domain-containing protein -
IL310_RS00470 (IL310_00475) 85362..85997 + 636 WP_168784595.1 DUF421 domain-containing protein -
IL310_RS00475 (IL310_00480) 86075..86356 + 282 WP_201249132.1 LapA family protein -
IL310_RS00480 (IL310_00485) 86379..86753 + 375 WP_058212039.1 large-conductance mechanosensitive channel protein MscL -
IL310_RS00485 (IL310_00490) 87039..87356 + 318 WP_058212038.1 SemiSWEET family transporter -
IL310_RS00490 (IL310_00495) 87560..87946 + 387 WP_201249021.1 DUF2798 domain-containing protein -
IL310_RS00495 (IL310_00500) 88297..88815 + 519 WP_201249022.1 hypothetical protein -
IL310_RS00500 (IL310_00505) 88875..89759 - 885 WP_201249023.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IL310_RS00505 (IL310_00510) 89781..90650 - 870 WP_201249024.1 hypothetical protein Antitoxin
IL310_RS00510 (IL310_00515) 90859..91554 - 696 WP_201249025.1 hypothetical protein -
IL310_RS00515 (IL310_00520) 91600..92571 - 972 WP_201249026.1 hypothetical protein -
IL310_RS00520 (IL310_00525) 93327..93689 + 363 WP_201249028.1 aldo/keto reductase -
IL310_RS00525 (IL310_00530) 94355..94843 + 489 WP_201249029.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..107451 107451


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(30-233)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 295 a.a.        Molecular weight: 35013.23 Da        Isoelectric Point: 5.9002

>T271211 WP_201249023.1 NZ_CP117405:c89759-88875 [Lactococcus lactis]
MNSNRLKDLIKNQDTSISSEEYRIRYATERFLLRVQRSSYRDKLILKGGFLLGTLFKVEQRTTKDLDTLITELSVSREQV
ETMLESIIQIDLNDNVKFELIKLIDSQQRRIYDGFKAKLKMNFLDERTFVNFDLDLGVGDTITPEAKKINIPLLFNEVKG
EKTEIALLAYPLETILAEKTEIILNLGTNNSRMKDFYDMHLLLNDPRKPDNELLYQAFENTWIFRHPNLSIDNERFEDWY
YVIESILENDKMNSISWHNYIKDRLYAKDLNLKNIVLQFKRYLEELEKVYIKRK

Download         Length: 885 bp

Antitoxin


Download         Length: 290 a.a.        Molecular weight: 34297.45 Da        Isoelectric Point: 8.7369

>AT271211 WP_201249024.1 NZ_CP117405:c90650-89781 [Lactococcus lactis]
MYSTIYDVFINNIDKSEEEKKNMIHEMVDIMDIDQLSKVIDFLKEPYFLKKLKPYLVNDMLPPIESPEFLFLLQLAKYNG
NLVKKLARENKLSDYYIDKFINKYRLREVSKSIYVFPGNEIDGNFVFQAQYTRSVISHETALYMHDLSDVIPRKTIMSMP
ISYKLSQVEKNERKYIKVHKEVLGSNRTYYVVEYYQNDPIYLMKNQPIGNSQIQLMNTQQGNEVRVTSVERTIADIFKPS
SNVEEEVKETALEQYSKRGNYDKSRLLRISKQQNVEKEIEHTLWKLKLH

Download         Length: 870 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References