Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yeeUV (cbtA-cbeA)/CbtA-CbeA |
Location | 4325636..4326471 | Replicon | chromosome |
Accession | NZ_CP117404 | ||
Organism | Salmonella enterica subsp. enterica serovar Typhimurium strain RM085 |
Toxin (Protein)
Gene name | yeeV | Uniprot ID | A0A1V1GYU4 |
Locus tag | PQQ07_RS21070 | Protein ID | WP_000854719.1 |
Coordinates | 4326094..4326471 (+) | Length | 126 a.a. |
Antitoxin (Protein)
Gene name | yeeU | Uniprot ID | - |
Locus tag | PQQ07_RS21065 | Protein ID | WP_001285113.1 |
Coordinates | 4325636..4326004 (+) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PQQ07_RS21025 (4320753) | 4320753..4321637 | + | 885 | WP_000010398.1 | 50S ribosome-binding GTPase | - |
PQQ07_RS21030 (4321755) | 4321755..4322432 | + | 678 | WP_001097369.1 | hypothetical protein | - |
PQQ07_RS21035 (4322438) | 4322438..4322671 | + | 234 | WP_001278282.1 | DUF905 family protein | - |
PQQ07_RS21040 (4322761) | 4322761..4323579 | + | 819 | WP_001175145.1 | DUF932 domain-containing protein | - |
PQQ07_RS21045 (4323656) | 4323656..4324141 | + | 486 | WP_000213705.1 | antirestriction protein | - |
PQQ07_RS21050 (4324157) | 4324157..4324633 | + | 477 | WP_001186715.1 | RadC family protein | - |
PQQ07_RS21055 (4324702) | 4324702..4324923 | + | 222 | WP_000692345.1 | DUF987 domain-containing protein | - |
PQQ07_RS21060 (4324942) | 4324942..4325586 | + | 645 | WP_000086770.1 | hypothetical protein | - |
PQQ07_RS21065 (4325636) | 4325636..4326004 | + | 369 | WP_001285113.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
PQQ07_RS21070 (4326094) | 4326094..4326471 | + | 378 | WP_000854719.1 | TA system toxin CbtA family protein | Toxin |
PQQ07_RS21075 (4326468) | 4326468..4326956 | + | 489 | WP_000761679.1 | DUF5983 family protein | - |
PQQ07_RS21080 (4326974) | 4326974..4327171 | + | 198 | WP_000839266.1 | DUF957 domain-containing protein | - |
PQQ07_RS21085 (4327256) | 4327256..4328101 | + | 846 | WP_001440175.1 | DUF4942 domain-containing protein | - |
PQQ07_RS21090 (4328170) | 4328170..4328565 | + | 396 | WP_000208386.1 | DUF6088 family protein | - |
PQQ07_RS21095 (4328558) | 4328558..4329505 | + | 948 | WP_001440173.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
PQQ07_RS21100 (4329791) | 4329791..4329868 | - | 78 | Protein_4123 | helix-turn-helix domain-containing protein | - |
PQQ07_RS21105 (4329959) | 4329959..4330291 | - | 333 | WP_001165471.1 | MerR family transcriptional regulator | - |
PQQ07_RS21110 (4330363) | 4330363..4330740 | + | 378 | WP_000916345.1 | EthD family reductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | floR | - | 4300626..4336875 | 36249 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 126 a.a. Molecular weight: 14059.10 Da Isoelectric Point: 8.2904
>T271206 WP_000854719.1 NZ_CP117404:4326094-4326471 [Salmonella enterica subsp. enterica serovar Typhimurium]
MKTLPDTHVREASRCPSPVTIWQILLSRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SACTRSQLINSIDILRARRATGLMARDNYRTVNNITLGKHPGAKQ
MKTLPDTHVREASRCPSPVTIWQILLSRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SACTRSQLINSIDILRARRATGLMARDNYRTVNNITLGKHPGAKQ
Download Length: 378 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13693.33 Da Isoelectric Point: 5.4970
>AT271206 WP_001285113.1 NZ_CP117404:4325636-4326004 [Salmonella enterica subsp. enterica serovar Typhimurium]
VSDSLHETNYPDDNNDRPWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSG
ELSPRHQHTVTLYARGLTCEADTLGSCGYVYLAVYPTSETKT
VSDSLHETNYPDDNNDRPWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSG
ELSPRHQHTVTLYARGLTCEADTLGSCGYVYLAVYPTSETKT
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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