Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2019362..2019505 Replicon chromosome
Accession NZ_CP117396
Organism Salmonella enterica subsp. enterica serovar Uganda strain RM016

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019400..2019503 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2019362..2019505 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP86_RS09735 2015786..2016484 - 699 WP_000944279.1 exodeoxyribonuclease X -
PQP86_RS09740 2016508..2017164 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
PQP86_RS09745 2017272..2017502 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PQP86_RS09750 2017640..2018014 + 375 WP_000168393.1 CopC domain-containing protein YobA -
PQP86_RS09755 2018015..2018890 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
PQP86_RS09760 2018907..2019260 + 354 WP_000722370.1 YebY family protein -
- 2019362..2019505 - 144 - - Antitoxin
- 2019400..2019503 + 104 - - Toxin
PQP86_RS09765 2019633..2020474 - 842 Protein_1906 tyrosine-type recombinase/integrase -
PQP86_RS09770 2020565..2020921 + 357 WP_000003145.1 hypothetical protein -
PQP86_RS09775 2020875..2021081 + 207 Protein_1908 phage tail protein -
PQP86_RS09780 2021253..2021408 + 156 Protein_1909 phage tail protein -
PQP86_RS09785 2021514..2021846 + 333 WP_031609875.1 DUF1353 domain-containing protein -
PQP86_RS09790 2021895..2022004 + 110 Protein_1911 tail fiber assembly protein -
PQP86_RS09795 2022095..2022280 - 186 WP_012218702.1 PagK family vesicle-borne virulence factor -
PQP86_RS09800 2022523..2022720 - 198 Protein_1913 tail fiber assembly protein -
PQP86_RS09805 2022716..2023486 - 771 WP_001652627.1 transporter substrate-binding domain-containing protein -
PQP86_RS09810 2023977..2024105 + 129 Protein_1915 helix-turn-helix domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2013700..2045928 32228
- inside Prophage - sopE2 2012023..2058853 46830


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T271120 NZ_CP117396:2019400-2019503 [Salmonella enterica subsp. enterica serovar Uganda]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT271120 NZ_CP117396:c2019505-2019362 [Salmonella enterica subsp. enterica serovar Uganda]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References