Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2019252..2019395 Replicon chromosome
Accession NZ_CP117394
Organism Salmonella enterica subsp. enterica serovar Uganda strain RM017

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019290..2019393 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2019252..2019395 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP77_RS09740 2015676..2016374 - 699 WP_000944279.1 exodeoxyribonuclease X -
PQP77_RS09745 2016398..2017054 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
PQP77_RS09750 2017162..2017392 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PQP77_RS09755 2017530..2017904 + 375 WP_000168393.1 CopC domain-containing protein YobA -
PQP77_RS09760 2017905..2018780 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
PQP77_RS09765 2018797..2019150 + 354 WP_000722370.1 YebY family protein -
- 2019252..2019395 - 144 - - Antitoxin
- 2019290..2019393 + 104 - - Toxin
PQP77_RS09770 2019523..2020364 - 842 Protein_1907 tyrosine-type recombinase/integrase -
PQP77_RS09775 2020455..2020811 + 357 WP_000003145.1 hypothetical protein -
PQP77_RS09780 2020765..2020971 + 207 Protein_1909 phage tail protein -
PQP77_RS09785 2021143..2021298 + 156 Protein_1910 phage tail protein -
PQP77_RS09790 2021404..2021736 + 333 WP_031609875.1 DUF1353 domain-containing protein -
PQP77_RS09795 2021785..2021894 + 110 Protein_1912 tail fiber assembly protein -
PQP77_RS09800 2021985..2022170 - 186 WP_012218702.1 PagK family vesicle-borne virulence factor -
PQP77_RS09805 2022413..2022610 - 198 Protein_1914 tail fiber assembly protein -
PQP77_RS09810 2022606..2023376 - 771 WP_001652627.1 transporter substrate-binding domain-containing protein -
PQP77_RS09815 2023867..2023995 + 129 Protein_1916 helix-turn-helix domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2013590..2045813 32223


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T271098 NZ_CP117394:2019290-2019393 [Salmonella enterica subsp. enterica serovar Uganda]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT271098 NZ_CP117394:c2019395-2019252 [Salmonella enterica subsp. enterica serovar Uganda]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References