Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2019506..2019649 Replicon chromosome
Accession NZ_CP117384
Organism Salmonella enterica subsp. enterica serovar Uganda strain RM013

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019544..2019647 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2019506..2019649 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP89_RS09735 2015930..2016628 - 699 WP_000944279.1 exodeoxyribonuclease X -
PQP89_RS09740 2016652..2017308 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
PQP89_RS09745 2017416..2017646 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PQP89_RS09750 2017784..2018158 + 375 WP_000168393.1 CopC domain-containing protein YobA -
PQP89_RS09755 2018159..2019034 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
PQP89_RS09760 2019051..2019404 + 354 WP_000722370.1 YebY family protein -
- 2019506..2019649 - 144 - - Antitoxin
- 2019544..2019647 + 104 - - Toxin
PQP89_RS09765 2019777..2020618 - 842 Protein_1906 tyrosine-type recombinase/integrase -
PQP89_RS09770 2020709..2021065 + 357 WP_000003145.1 hypothetical protein -
PQP89_RS09775 2021019..2021225 + 207 Protein_1908 phage tail protein -
PQP89_RS09780 2021397..2021552 + 156 Protein_1909 phage tail protein -
PQP89_RS09785 2021658..2021990 + 333 WP_031609875.1 DUF1353 domain-containing protein -
PQP89_RS09790 2022039..2022148 + 110 Protein_1911 tail fiber assembly protein -
PQP89_RS09795 2022239..2022424 - 186 WP_012218702.1 PagK family vesicle-borne virulence factor -
PQP89_RS09800 2022667..2022864 - 198 Protein_1913 tail fiber assembly protein -
PQP89_RS09805 2022860..2023630 - 771 WP_001652627.1 transporter substrate-binding domain-containing protein -
PQP89_RS09810 2024121..2024249 + 129 Protein_1915 helix-turn-helix domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2013844..2046071 32227


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T270997 NZ_CP117384:2019544-2019647 [Salmonella enterica subsp. enterica serovar Uganda]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT270997 NZ_CP117384:c2019649-2019506 [Salmonella enterica subsp. enterica serovar Uganda]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References