Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2019187..2019330 Replicon chromosome
Accession NZ_CP117382
Organism Salmonella enterica subsp. enterica serovar Uganda strain RM018

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019225..2019328 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2019187..2019330 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP98_RS09725 2015611..2016309 - 699 WP_000944279.1 exodeoxyribonuclease X -
PQP98_RS09730 2016333..2016989 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
PQP98_RS09735 2017097..2017327 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PQP98_RS09740 2017465..2017839 + 375 WP_000168393.1 CopC domain-containing protein YobA -
PQP98_RS09745 2017840..2018715 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
PQP98_RS09750 2018732..2019085 + 354 WP_000722370.1 YebY family protein -
- 2019187..2019330 - 144 - - Antitoxin
- 2019225..2019328 + 104 - - Toxin
PQP98_RS09755 2019458..2020299 - 842 Protein_1904 tyrosine-type recombinase/integrase -
PQP98_RS09760 2020390..2020746 + 357 WP_000003145.1 hypothetical protein -
PQP98_RS09765 2020700..2020906 + 207 Protein_1906 phage tail protein -
PQP98_RS09770 2021078..2021233 + 156 Protein_1907 phage tail protein -
PQP98_RS09775 2021339..2021671 + 333 WP_031609875.1 DUF1353 domain-containing protein -
PQP98_RS09780 2021720..2021829 + 110 Protein_1909 tail fiber assembly protein -
PQP98_RS09785 2021920..2022105 - 186 WP_012218702.1 PagK family vesicle-borne virulence factor -
PQP98_RS09790 2022348..2022545 - 198 Protein_1911 tail fiber assembly protein -
PQP98_RS09795 2022541..2023311 - 771 WP_001652627.1 transporter substrate-binding domain-containing protein -
PQP98_RS09800 2023802..2023930 + 129 Protein_1913 helix-turn-helix domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2013525..2045753 32228
- inside Prophage - sopE2 2011848..2048362 36514


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T270975 NZ_CP117382:2019225-2019328 [Salmonella enterica subsp. enterica serovar Uganda]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT270975 NZ_CP117382:c2019330-2019187 [Salmonella enterica subsp. enterica serovar Uganda]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References