Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2162264..2162409 Replicon chromosome
Accession NZ_CP117380
Organism Salmonella enterica subsp. enterica serovar Newport strain RM037

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2162266..2162369 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2162264..2162409 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP93_RS10835 2157554..2157898 - 345 Protein_2123 macro domain-containing protein -
PQP93_RS10840 2158113..2158373 - 261 Protein_2124 DUF1441 family protein -
PQP93_RS10845 2158428..2158616 + 189 WP_274890301.1 hypothetical protein -
PQP93_RS10850 2158681..2158848 + 168 WP_000789530.1 lytic enzyme -
PQP93_RS10855 2159105..2159639 - 535 Protein_2127 DUF2514 domain-containing protein -
PQP93_RS10860 2159636..2159884 - 249 Protein_2128 glycoside hydrolase family 19 protein -
PQP93_RS10865 2160032..2161027 + 996 Protein_2129 PD-(D/E)XK nuclease-like domain-containing protein -
PQP93_RS10870 2161057..2162136 + 1080 WP_000087646.1 phage integrase Arm DNA-binding domain-containing protein -
- 2162264..2162409 + 146 - - Antitoxin
- 2162266..2162369 - 104 - - Toxin
PQP93_RS10875 2162509..2162862 - 354 WP_000722368.1 YebY family protein -
PQP93_RS10880 2162879..2163754 - 876 WP_000979684.1 copper homeostasis membrane protein CopD -
PQP93_RS10885 2163755..2164129 - 375 WP_000168395.1 CopC domain-containing protein YobA -
PQP93_RS10890 2164267..2164497 + 231 WP_000856224.1 DNA polymerase III subunit theta -
PQP93_RS10895 2164605..2165261 + 657 WP_000100249.1 carbon-nitrogen hydrolase family protein -
PQP93_RS10900 2165285..2165983 + 699 WP_000944285.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2130162..2168071 37909
- inside Prophage - sopE2 2122509..2184280 61771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T270959 NZ_CP117380:c2162369-2162266 [Salmonella enterica subsp. enterica serovar Newport]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT270959 NZ_CP117380:2162264-2162409 [Salmonella enterica subsp. enterica serovar Newport]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References