Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2045455..2045600 Replicon chromosome
Accession NZ_CP117378
Organism Salmonella enterica subsp. enterica serovar Newport strain RM038

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2045495..2045598 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2045455..2045600 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP81_RS09890 2041881..2042579 - 699 WP_000944285.1 exodeoxyribonuclease X -
PQP81_RS09895 2042603..2043259 - 657 WP_000100249.1 carbon-nitrogen hydrolase family protein -
PQP81_RS09900 2043367..2043597 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PQP81_RS09905 2043735..2044109 + 375 WP_000168395.1 CopC domain-containing protein YobA -
PQP81_RS09910 2044110..2044985 + 876 WP_000979684.1 copper homeostasis membrane protein CopD -
PQP81_RS09915 2045002..2045355 + 354 WP_000722368.1 YebY family protein -
- 2045455..2045600 - 146 - - Antitoxin
- 2045495..2045598 + 104 - - Toxin
PQP81_RS09920 2045728..2046807 - 1080 WP_000087646.1 phage integrase Arm DNA-binding domain-containing protein -
PQP81_RS09925 2046837..2047832 - 996 Protein_1938 PD-(D/E)XK nuclease-like domain-containing protein -
PQP81_RS09930 2047980..2048228 + 249 Protein_1939 glycoside hydrolase family 19 protein -
PQP81_RS09935 2048225..2048759 + 535 Protein_1940 DUF2514 domain-containing protein -
PQP81_RS09940 2049016..2049183 - 168 WP_000789530.1 lytic enzyme -
PQP81_RS09945 2049248..2049436 - 189 WP_001521334.1 hypothetical protein -
PQP81_RS09950 2049490..2049750 + 261 Protein_1943 DUF1441 family protein -
PQP81_RS09955 2049965..2050309 + 345 Protein_1944 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2025455..2085354 59899
- inside Prophage - sopE2 2023584..2085354 61770


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T270943 NZ_CP117378:2045495-2045598 [Salmonella enterica subsp. enterica serovar Newport]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT270943 NZ_CP117378:c2045600-2045455 [Salmonella enterica subsp. enterica serovar Newport]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References