Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 870298..870958 Replicon chromosome
Accession NZ_CP117370
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain RM054

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag PQP97_RS04240 Protein ID WP_000244756.1
Coordinates 870545..870958 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag PQP97_RS04235 Protein ID WP_000351186.1
Coordinates 870298..870564 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP97_RS04215 (866226) 866226..867659 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
PQP97_RS04220 (867818) 867818..868129 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
PQP97_RS04225 (868293) 868293..868952 + 660 WP_000250289.1 hemolysin III family protein -
PQP97_RS04230 (869068) 869068..870048 - 981 WP_000874172.1 tRNA-modifying protein YgfZ -
PQP97_RS04235 (870298) 870298..870564 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
PQP97_RS04240 (870545) 870545..870958 + 414 WP_000244756.1 protein YgfX Toxin
PQP97_RS04245 (871011) 871011..871532 - 522 WP_001055885.1 flavodoxin FldB -
PQP97_RS04250 (871645) 871645..872541 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
PQP97_RS04255 (872565) 872565..873278 + 714 WP_000745625.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PQP97_RS04260 (873284) 873284..875017 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T270870 WP_000244756.1 NZ_CP117370:870545-870958 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT270870 WP_000351186.1 NZ_CP117370:870298-870564 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References