Detailed information of TA system TA027087

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 3684195..3684672
• Replicon: chromosome
• Accession: NC_017584
• Organism: Rhodospirillum rubrum F11

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: Q2RPF4
• Locus tag: F11_RS16380
• Protein ID: WP_011390944.1
• Coordinates: 3684403..3684672 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: Q2RPF5
• Locus tag: F11_RS16375
• Protein ID: WP_011390943.1
• Coordinates: 3684195..3684419 (+)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F11_RS16350	3679306..3680265	+	960	WP_011390938.1	aspartate carbamoyltransferase catalytic subunit	-
F11_RS16355	3680265..3681563	+	1299	WP_011390939.1	dihydroorotase	-
F11_RS16360	3681556..3682206	+	651	WP_011390940.1	glycerol-3-phosphate 1-O-acyltransferase PlsY	-
F11_RS16365	3682303..3682971	+	669	WP_011390941.1	glutathione S-transferase family protein	-
F11_RS16370	3682974..3684098	+	1125	WP_011390942.1	DNA-processing protein DprA	-
F11_RS16375	3684195..3684419	+	225	WP_011390943.1	TraY domain-containing protein	Antitoxin
F11_RS16380	3684403..3684672	+	270	WP_011390944.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
F11_RS16385	3684708..3685028	-	321	WP_011390945.1	type II toxin-antitoxin system HicB family antitoxin	-
F11_RS16390	3685083..3685364	-	282	WP_011390946.1	type II toxin-antitoxin system HicA family toxin	-
F11_RS16395	3685626..3686633	+	1008	WP_014626531.1	ABC transporter substrate-binding protein	-
F11_RS16400	3686649..3688373	+	1725	WP_011390948.1	iron ABC transporter permease	-
F11_RS16405	3688361..3689440	+	1080	WP_011390949.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-88)

Antitoxin

• Relaxosome protein TraY (4-48)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10548.30 Da
• Isoelectric Point: 10.5999

>T27087 WP_011390944.1 NC_017584:3684403-3684672 [Rhodospirillum rubrum F11]
MTWKIEFDPSALRELDKLDPQIAARVLRFLRDRVAVLENPRSLGEALKGPRLGAFWKYRVSDYRIIAHIEDDTLRILVLR
IGNRREVYR

Nucleotide

• Length: 270 bp

>T27087 NC_017584:3684403-3684672 [Rhodospirillum rubrum F11]
ATGACCTGGAAGATTGAGTTTGATCCCTCGGCACTGCGCGAACTGGACAAACTCGACCCGCAGATCGCCGCGCGCGTTCT
TCGGTTTCTCCGTGACCGGGTCGCCGTTCTGGAGAACCCGCGCAGCCTCGGAGAGGCTCTGAAAGGCCCCCGGCTCGGCG
CGTTCTGGAAATATCGCGTGAGCGATTACCGGATCATCGCGCACATAGAAGACGACACCCTGCGCATCCTGGTTCTCCGC
ATCGGAAACCGTCGCGAAGTTTACCGATAG

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8437.57 Da
• Isoelectric Point: 4.4678

>AT27087 WP_011390943.1 NC_017584:3684195-3684419 [Rhodospirillum rubrum F11]
MLAIRLPAELETRLEALARATGRTKTFYVREAITAHLEDLEDFYLADQRLADLRAGATQTVALEDVLKRYDLED

Nucleotide

• Length: 225 bp

>AT27087 NC_017584:3684195-3684419 [Rhodospirillum rubrum F11]
ATGCTTGCGATTCGACTGCCCGCCGAATTGGAAACGCGCCTGGAGGCCCTGGCGCGCGCCACCGGCCGAACAAAAACATT
CTATGTCCGCGAGGCCATCACCGCCCATCTCGAAGACCTCGAGGATTTCTATCTCGCCGACCAGCGTCTGGCCGATCTGC
GGGCGGGCGCAACCCAGACCGTGGCGCTTGAAGACGTCCTGAAACGCTATGACCTGGAAGATTGA

Structures

Toxin

• AlphaFold DB: Q2RPF4

Antitoxin

• AlphaFold DB: Q2RPF5