Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 46390..46985 Replicon plasmid pSBAL11702
Accession NC_017580
Organism Shewanella baltica OS117

Toxin (Protein)


Gene name chpB Uniprot ID A0A7U3ZFM4
Locus tag SBAL117_RS23975 Protein ID WP_014620954.1
Coordinates 46644..46985 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID A0A7U3ZFS0
Locus tag SBAL117_RS23970 Protein ID WP_014620953.1
Coordinates 46390..46644 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBAL117_RS23945 42490..43494 + 1005 WP_014620948.1 hypothetical protein -
SBAL117_RS23950 43538..44107 + 570 WP_014620949.1 hypothetical protein -
SBAL117_RS23955 44107..44589 + 483 WP_014620950.1 hypothetical protein -
SBAL117_RS23960 44645..45574 + 930 WP_014620951.1 type II secretion system GspH family protein -
SBAL117_RS23965 45590..46285 + 696 WP_014620952.1 hypothetical protein -
SBAL117_RS23970 46390..46644 + 255 WP_014620953.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
SBAL117_RS23975 46644..46985 + 342 WP_014620954.1 type II toxin-antitoxin system ChpB family toxin Toxin
SBAL117_RS23980 47068..48060 + 993 WP_014620955.1 trypsin-like serine protease -
SBAL117_RS23985 48281..48967 + 687 WP_014620956.1 hypothetical protein -
SBAL117_RS23990 48964..49662 + 699 WP_014620957.1 TIGR03759 family integrating conjugative element protein -
SBAL117_RS23995 49671..50171 + 501 WP_131524925.1 hypothetical protein -
SBAL117_RS24000 50164..50571 + 408 WP_014620959.1 integrating conjugative element protein -
SBAL117_RS25740 50671..50844 + 174 WP_014620960.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..91728 91728


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-111)

Antitoxin

SpoVT-AbrB domain

(8-50)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 11752.78 Da        Isoelectric Point: 8.5534

>T27073 WP_014620954.1 NC_017580:46644-46985 [Shewanella baltica OS117]
MAGFDRGDIVLACLNPTVGSEIQGAMRPCLVLSTKPFNKLGLTLIAPISQGGNHARFNGFAVPLMGTGTETQGVVLANGI
RSIDLAARGAKRVEKAPKEVVNEVLAILAAILE

Download         Length: 342 bp

>T27073 NC_017580:46644-46985 [Shewanella baltica OS117]
ATGGCCGGATTTGATCGAGGTGATATTGTTCTAGCATGTTTAAATCCGACTGTTGGCAGTGAAATTCAAGGAGCAATGCG
ACCTTGCTTAGTGTTATCAACGAAGCCATTTAATAAGCTAGGGTTAACGCTAATAGCGCCTATCTCGCAAGGCGGTAATC
ATGCTCGCTTTAATGGCTTTGCTGTACCACTTATGGGGACTGGCACCGAAACGCAAGGTGTTGTGTTGGCAAATGGTATT
AGGTCGATAGATTTAGCCGCGAGAGGCGCAAAAAGGGTGGAAAAAGCGCCTAAAGAGGTCGTTAACGAAGTGTTGGCGAT
TTTGGCCGCTATCTTGGAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9140.56 Da        Isoelectric Point: 4.7361

>AT27073 WP_014620953.1 NC_017580:46390-46644 [Shewanella baltica OS117]
MTTTLRNIGNSKGVVVPAHLLKELDIQVGDTMEPAVENGKLVLTPTAKRQKYKLADLLAKCDESAPMPQELVEWDAAQPV
GNEI

Download         Length: 255 bp

>AT27073 NC_017580:46390-46644 [Shewanella baltica OS117]
ATGACTACAACACTACGCAATATCGGTAATTCAAAAGGGGTTGTTGTGCCCGCACACTTACTTAAGGAGCTAGATATTCA
AGTTGGCGATACTATGGAGCCGGCTGTTGAAAATGGCAAACTGGTATTGACACCAACAGCCAAGCGCCAAAAATACAAAC
TGGCAGACTTGTTGGCAAAGTGTGATGAATCCGCACCAATGCCGCAAGAGCTTGTGGAATGGGACGCCGCACAACCCGTC
GGGAATGAAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U3ZFM4

Antitoxin

Source ID Structure
AlphaFold DB A0A7U3ZFS0

References