27072

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 4347637..4348433 Replicon chromosome
Accession NC_017579
Organism Shewanella baltica OS117

Toxin (Protein)


Gene name - Uniprot ID A0A7U3ZE40
Locus tag SBAL117_RS19155 Protein ID WP_014620864.1
Coordinates 4347637..4348167 (-) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A7U4E2J7
Locus tag SBAL117_RS19160 Protein ID WP_014620865.1
Coordinates 4348164..4348433 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBAL117_RS19110 4343786..4344139 + 354 WP_012196661.1 hypothetical protein -
SBAL117_RS19115 4344136..4344396 + 261 WP_014620859.1 pyocin activator PrtN family protein -
SBAL117_RS19120 4344422..4344769 + 348 WP_011847795.1 hypothetical protein -
SBAL117_RS19125 4344800..4345078 + 279 WP_014620860.1 hypothetical protein -
SBAL117_RS19130 4345079..4345357 + 279 WP_014620861.1 hypothetical protein -
SBAL117_RS19135 4345354..4345584 + 231 WP_014620862.1 hypothetical protein -
SBAL117_RS19140 4345581..4345919 + 339 WP_014620863.1 hypothetical protein -
SBAL117_RS19150 4345947..4347502 + 1556 WP_086011359.1 IS3-like element ISSba13 family transposase -
SBAL117_RS19155 4347637..4348167 - 531 WP_014620864.1 GNAT family N-acetyltransferase Toxin
SBAL117_RS19160 4348164..4348433 - 270 WP_014620865.1 DUF1778 domain-containing protein Antitoxin
SBAL117_RS19165 4348607..4349056 - 450 WP_148258310.1 hypothetical protein -
SBAL117_RS19170 4349066..4349497 - 432 WP_041409006.1 hypothetical protein -
SBAL117_RS19175 4349638..4350333 - 696 WP_014620868.1 hypothetical protein -
SBAL117_RS19180 4350443..4350928 - 486 WP_014620869.1 hypothetical protein -
SBAL117_RS19185 4351578..4352252 - 675 WP_011847807.1 Fe2+-dependent dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4305642..4404775 99133


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(96-155)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19768.04 Da        Isoelectric Point: 8.3253

>T27072 WP_014620864.1 NC_017579:c4348167-4347637 [Shewanella baltica OS117]
VSYSKTFKELDNSQYDRASFDCGEAELNDFIQTQAAKHMQAGISRTMVLPAVTPLPNQKYPICSFYTIAPSSICRDILPQ
AMGKKLLRYPIPVFLLAQLAVHKEFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
RVRMFIPMKTVGQLFT

Download         Length: 531 bp

>T27072 NC_017579:c4348167-4347637 [Shewanella baltica OS117]
GTGAGTTATTCCAAAACTTTCAAAGAATTGGATAACTCACAATACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCAGCGAAACACATGCAAGCAGGTATTAGCCGTACAATGGTTTTACCTGCTGTTACGC
CATTACCCAATCAAAAATATCCAATTTGCTCTTTCTATACTATCGCACCAAGTTCAATTTGCCGTGATATCTTGCCGCAA
GCCATGGGTAAAAAGTTACTACGCTATCCCATTCCGGTCTTTCTGCTTGCTCAACTTGCTGTCCATAAAGAGTTTCATGG
TAGTGGGTTAGGTAAAGCTAGCTTAATCAAAGCGCTAGAATATCTTTGGGAAATTAACGCTCACATGAGAGCTTATGCCA
TTGTTGTCGATTGCTTAACTGGCCAAGCTGAATCATTTTACGCTAAGTATGGTTTCGAGGTTCTTTGTGAAATCAACGGT
CGTGTCAGAATGTTTATTCCAATGAAAACAGTCGGTCAGTTATTCACTTAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9903.38 Da        Isoelectric Point: 4.9059

>AT27072 WP_014620865.1 NC_017579:c4348433-4348164 [Shewanella baltica OS117]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESITVKADVFDQFLMACDEAKAPNKALREAA
AFTKRGEFK

Download         Length: 270 bp

>AT27072 NC_017579:c4348433-4348164 [Shewanella baltica OS117]
ATGGCGACTGCAAGACTTGATATCCGTTTGGATGAAGAAATCAAAGCTAAGGCTGAGAAAGCATCGGCTTTGCTTGGTTT
AAAAAGCTTAACTGAATACGTCGTTCGCTTAATGGACGAAGATTCAACTCAGGTGATTGCTGAGCACGAAAGCATTACTG
TTAAAGCTGATGTATTCGACCAATTCTTAATGGCTTGTGATGAGGCTAAGGCCCCGAACAAGGCATTACGTGAAGCGGCT
GCATTTACTAAACGTGGTGAGTTTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U3ZE40

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4E2J7

References