Detailed information of TA system TA027071

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 1477404..1478046
• Replicon: chromosome
• Accession: NC_017579
• Organism: Shewanella baltica OS117

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: A3D1U8
• Locus tag: SBAL117_RS06480
• Protein ID: WP_011846165.1
• Coordinates: 1477633..1478046 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: SBAL117_RS06475
• Protein ID: WP_006080770.1
• Coordinates: 1477404..1477652 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SBAL117_RS06450	1473060..1473869	+	810	WP_011846160.1	prolipoprotein diacylglyceryl transferase	-
SBAL117_RS06455	1473866..1474660	+	795	WP_011846161.1	thymidylate synthase	-
SBAL117_RS06460	1474778..1475947	+	1170	WP_011846162.1	Na+/H+ antiporter NhaA	-
SBAL117_RS06465	1475950..1476336	+	387	WP_006080768.1	hypothetical protein	-
SBAL117_RS06470	1476410..1477318	+	909	WP_006085064.1	transcriptional activator NhaR	-
SBAL117_RS06475	1477404..1477652	+	249	WP_006080770.1	succinate dehydrogenase assembly factor 2	Antitoxin
SBAL117_RS06480	1477633..1478046	+	414	WP_011846165.1	hypothetical protein	Toxin
SBAL117_RS06485	1478133..1479746	-	1614	WP_006080772.1	L-aspartate oxidase	-
SBAL117_RS06490	1479937..1480515	+	579	WP_006080773.1	RNA polymerase sigma factor RpoE	-
SBAL117_RS06495	1480557..1481183	+	627	WP_011846166.1	anti-sigma factor	-
SBAL117_RS06500	1481196..1482128	+	933	WP_011846167.1	MucB/RseB C-terminal domain-containing protein	-
SBAL117_RS06505	1482139..1482612	+	474	WP_011846168.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (6-135)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 16265.22 Da
• Isoelectric Point: 7.6686

>T27071 WP_011846165.1 NC_017579:1477633-1478046 [Shewanella baltica OS117]
VEDRHHSFSVKASFDQRLSLVVFICVCSSSFLLWPQSDNLAISLLKYLFILLVCVFLLSQMWRLQYWRLDFVLSDKGEGR
LSTGEHFQVLKRTWVTPFVCLMYIEVDTQLRLLMVWADMLDDTDYRHLCRLLLRAKI

Nucleotide

• Length: 414 bp

>T27071 NC_017579:1477633-1478046 [Shewanella baltica OS117]
GTGGAAGACCGGCACCATAGTTTCAGCGTAAAAGCCTCCTTCGACCAACGACTCTCGTTGGTCGTTTTTATTTGTGTCTG
TTCTAGCTCATTTCTGCTCTGGCCTCAAAGCGATAATCTCGCCATATCCCTGCTTAAATATCTGTTTATCCTGCTAGTTT
GTGTTTTCTTGCTATCACAGATGTGGCGACTGCAGTATTGGCGTTTAGATTTTGTGCTTAGTGATAAAGGCGAGGGACGT
TTGTCAACGGGTGAGCACTTTCAGGTATTAAAGCGAACTTGGGTGACACCCTTTGTTTGCTTGATGTATATCGAAGTGGA
TACTCAGTTGCGGCTCTTGATGGTTTGGGCGGATATGCTAGACGATACTGACTATCGGCATTTATGTCGGCTGTTGCTGC
GGGCTAAAATATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9723.36 Da
• Isoelectric Point: 4.4929

>AT27071 WP_006080770.1 NC_017579:1477404-1477652 [Shewanella baltica OS117]
MELMNIARVRWACRRGMLELDVLFQPFVENFYQEMSDEDKTVFIRLLECEDPELFAWFMGHEVCPDAELARMVVKVRGRP
AP

Nucleotide

• Length: 249 bp

>AT27071 NC_017579:1477404-1477652 [Shewanella baltica OS117]
TTGGAATTAATGAACATCGCAAGGGTTCGCTGGGCATGTCGCCGCGGGATGCTGGAATTAGACGTTTTGTTTCAACCTTT
TGTTGAAAATTTCTATCAAGAAATGTCCGATGAAGATAAAACCGTGTTTATCCGTTTGTTGGAATGTGAAGATCCCGAAT
TGTTTGCTTGGTTTATGGGCCATGAAGTGTGCCCTGATGCTGAGCTTGCGCGCATGGTAGTGAAAGTCCGTGGAAGACCG
GCACCATAG

Structures

Toxin

• AlphaFold DB: A3D1U8