Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | sanaTA/AbiEii-DUF6088 |
Location | 32854..34202 | Replicon | plasmid pSBAL11703 |
Accession | NC_017578 | ||
Organism | Shewanella baltica OS117 |
Toxin (Protein)
Gene name | sanaT | Uniprot ID | A0A7U4E3J6 |
Locus tag | SBAL117_RS24430 | Protein ID | WP_014620448.1 |
Coordinates | 33261..34202 (+) | Length | 314 a.a. |
Antitoxin (Protein)
Gene name | sanaA | Uniprot ID | A3DB89 |
Locus tag | SBAL117_RS24425 | Protein ID | WP_006087348.1 |
Coordinates | 32854..33264 (+) | Length | 137 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SBAL117_RS24405 | 29561..29812 | + | 252 | Protein_33 | transposase | - |
SBAL117_RS25275 | 29748..30056 | - | 309 | Protein_34 | recombinase family protein | - |
SBAL117_RS24410 | 30760..31083 | + | 324 | WP_011840013.1 | hypothetical protein | - |
SBAL117_RS24415 | 31126..31761 | + | 636 | WP_011840014.1 | SDR family NAD(P)-dependent oxidoreductase | - |
SBAL117_RS24420 | 32025..32636 | + | 612 | WP_014620447.1 | recombinase family protein | - |
SBAL117_RS24425 | 32854..33264 | + | 411 | WP_006087348.1 | hypothetical protein | Antitoxin |
SBAL117_RS24430 | 33261..34202 | + | 942 | WP_014620448.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
SBAL117_RS24435 | 34210..36801 | + | 2592 | WP_014620449.1 | type I restriction-modification system subunit M | - |
SBAL117_RS25280 | 36803..37969 | + | 1167 | WP_014620450.1 | restriction endonuclease subunit S | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..71173 | 71173 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 314 a.a. Molecular weight: 35799.78 Da Isoelectric Point: 7.0963
>T27069 WP_014620448.1 NC_017578:33261-34202 [Shewanella baltica OS117]
MKKLKQQFLEVSDALALGNPAIIEKDYWVVALLSELEQLTFETHQMVFSGGTALAKSNVKILRMSEDVDIKLIPTPQFQH
LSRGRKKQYRKALAVQIETAIIASNKFSIEARLVQDEYRYVEYELKYPQQFSQAPCLRPIIKLELMETIPLLALETRGIQ
SLVAELYKLPQEVNGFICVSVNTTLVEKVLSMLRRTMSVKRDAARNDDVTLIRHIYDVHCIHAALALDNKLLAPLFLAVL
AEDIARFGNQHAEFVMDPTNELRLGLLELENNPLFRQRFDDFVKPMVFNSQSPNFDTCFMSFKHIATSLILTI
MKKLKQQFLEVSDALALGNPAIIEKDYWVVALLSELEQLTFETHQMVFSGGTALAKSNVKILRMSEDVDIKLIPTPQFQH
LSRGRKKQYRKALAVQIETAIIASNKFSIEARLVQDEYRYVEYELKYPQQFSQAPCLRPIIKLELMETIPLLALETRGIQ
SLVAELYKLPQEVNGFICVSVNTTLVEKVLSMLRRTMSVKRDAARNDDVTLIRHIYDVHCIHAALALDNKLLAPLFLAVL
AEDIARFGNQHAEFVMDPTNELRLGLLELENNPLFRQRFDDFVKPMVFNSQSPNFDTCFMSFKHIATSLILTI
Download Length: 942 bp
>T27069 NC_017578:33261-34202 [Shewanella baltica OS117]
ATGAAAAAACTGAAACAACAGTTCTTAGAGGTTTCCGATGCATTAGCGCTCGGGAACCCCGCCATAATTGAAAAAGATTA
TTGGGTGGTTGCTCTACTTTCAGAGCTTGAACAGCTAACGTTTGAAACTCATCAAATGGTGTTTTCCGGCGGCACCGCAC
TTGCTAAGTCCAATGTTAAAATACTTCGAATGTCTGAAGACGTGGACATAAAGCTGATCCCCACGCCGCAATTTCAACAC
CTTAGTCGCGGCAGGAAAAAACAGTACCGTAAAGCGTTAGCAGTACAAATTGAAACAGCGATTATTGCATCTAACAAATT
TTCTATCGAAGCTAGATTAGTTCAGGATGAATATCGCTATGTGGAATATGAGCTTAAATATCCACAACAATTTAGCCAGG
CTCCTTGTCTACGCCCAATCATCAAGTTAGAACTGATGGAGACAATTCCACTTCTTGCGCTGGAAACACGGGGCATTCAA
TCGTTAGTAGCAGAACTTTATAAGCTGCCACAAGAAGTGAACGGATTCATCTGTGTATCAGTAAATACCACCTTGGTGGA
GAAAGTGCTTTCCATGCTACGCCGTACAATGTCAGTTAAGCGTGATGCAGCGCGAAACGATGACGTCACCTTAATTCGAC
ATATTTACGACGTACACTGTATTCATGCAGCACTGGCCCTTGATAATAAATTACTCGCGCCCCTTTTCCTCGCCGTATTA
GCAGAAGATATTGCTCGCTTTGGCAACCAACATGCCGAATTCGTCATGGACCCAACCAATGAGTTACGCCTTGGCTTACT
GGAGCTAGAAAACAACCCACTCTTCCGACAACGCTTTGATGATTTTGTTAAACCAATGGTGTTTAACTCGCAATCACCCA
ATTTTGATACGTGCTTTATGTCCTTTAAACATATTGCGACATCACTCATTCTGACTATTTAG
ATGAAAAAACTGAAACAACAGTTCTTAGAGGTTTCCGATGCATTAGCGCTCGGGAACCCCGCCATAATTGAAAAAGATTA
TTGGGTGGTTGCTCTACTTTCAGAGCTTGAACAGCTAACGTTTGAAACTCATCAAATGGTGTTTTCCGGCGGCACCGCAC
TTGCTAAGTCCAATGTTAAAATACTTCGAATGTCTGAAGACGTGGACATAAAGCTGATCCCCACGCCGCAATTTCAACAC
CTTAGTCGCGGCAGGAAAAAACAGTACCGTAAAGCGTTAGCAGTACAAATTGAAACAGCGATTATTGCATCTAACAAATT
TTCTATCGAAGCTAGATTAGTTCAGGATGAATATCGCTATGTGGAATATGAGCTTAAATATCCACAACAATTTAGCCAGG
CTCCTTGTCTACGCCCAATCATCAAGTTAGAACTGATGGAGACAATTCCACTTCTTGCGCTGGAAACACGGGGCATTCAA
TCGTTAGTAGCAGAACTTTATAAGCTGCCACAAGAAGTGAACGGATTCATCTGTGTATCAGTAAATACCACCTTGGTGGA
GAAAGTGCTTTCCATGCTACGCCGTACAATGTCAGTTAAGCGTGATGCAGCGCGAAACGATGACGTCACCTTAATTCGAC
ATATTTACGACGTACACTGTATTCATGCAGCACTGGCCCTTGATAATAAATTACTCGCGCCCCTTTTCCTCGCCGTATTA
GCAGAAGATATTGCTCGCTTTGGCAACCAACATGCCGAATTCGTCATGGACCCAACCAATGAGTTACGCCTTGGCTTACT
GGAGCTAGAAAACAACCCACTCTTCCGACAACGCTTTGATGATTTTGTTAAACCAATGGTGTTTAACTCGCAATCACCCA
ATTTTGATACGTGCTTTATGTCCTTTAAACATATTGCGACATCACTCATTCTGACTATTTAG
Antitoxin
Download Length: 137 a.a. Molecular weight: 15505.88 Da Isoelectric Point: 10.3652
>AT27069 WP_006087348.1 NC_017578:32854-33264 [Shewanella baltica OS117]
MAAVDSIFQKIKRSRRYVFERKDFDGIASYDQIGRSLNQLMDRGEIMKLGYGLYTKARVNSLTGRLMPTCPGGSDALMRE
ILKMKDIDFEIDNLSLQSLSGKNTQIPSSVHYSWDQKQFNRKLVVGNRLLTPASRP
MAAVDSIFQKIKRSRRYVFERKDFDGIASYDQIGRSLNQLMDRGEIMKLGYGLYTKARVNSLTGRLMPTCPGGSDALMRE
ILKMKDIDFEIDNLSLQSLSGKNTQIPSSVHYSWDQKQFNRKLVVGNRLLTPASRP
Download Length: 411 bp
>AT27069 NC_017578:32854-33264 [Shewanella baltica OS117]
ATGGCAGCTGTTGACAGTATCTTTCAAAAAATAAAGCGTTCTAGACGCTACGTTTTCGAACGCAAAGACTTTGACGGCAT
TGCTAGCTATGACCAGATTGGCAGATCGCTTAACCAGTTAATGGATAGAGGCGAGATAATGAAGCTTGGCTATGGCTTAT
ACACTAAAGCGCGAGTAAATAGCCTGACAGGACGTTTAATGCCGACCTGTCCAGGTGGTAGCGATGCACTTATGCGTGAA
ATATTGAAAATGAAAGACATCGATTTCGAGATAGATAATCTGTCCTTACAAAGTCTTTCCGGTAAAAACACCCAAATTCC
CTCATCAGTTCATTACTCATGGGATCAAAAACAGTTCAATCGAAAATTGGTTGTTGGTAACAGACTGTTGACGCCAGCAA
GTAGACCATGA
ATGGCAGCTGTTGACAGTATCTTTCAAAAAATAAAGCGTTCTAGACGCTACGTTTTCGAACGCAAAGACTTTGACGGCAT
TGCTAGCTATGACCAGATTGGCAGATCGCTTAACCAGTTAATGGATAGAGGCGAGATAATGAAGCTTGGCTATGGCTTAT
ACACTAAAGCGCGAGTAAATAGCCTGACAGGACGTTTAATGCCGACCTGTCCAGGTGGTAGCGATGCACTTATGCGTGAA
ATATTGAAAATGAAAGACATCGATTTCGAGATAGATAATCTGTCCTTACAAAGTCTTTCCGGTAAAAACACCCAAATTCC
CTCATCAGTTCATTACTCATGGGATCAAAAACAGTTCAATCGAAAATTGGTTGTTGGTAACAGACTGTTGACGCCAGCAA
GTAGACCATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U4E3J6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A3DB89 |