27069

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 32854..34202 Replicon plasmid pSBAL11703
Accession NC_017578
Organism Shewanella baltica OS117

Toxin (Protein)


Gene name sanaT Uniprot ID A0A7U4E3J6
Locus tag SBAL117_RS24430 Protein ID WP_014620448.1
Coordinates 33261..34202 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A3DB89
Locus tag SBAL117_RS24425 Protein ID WP_006087348.1
Coordinates 32854..33264 (+) Length 137 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBAL117_RS24405 29561..29812 + 252 Protein_33 transposase -
SBAL117_RS25275 29748..30056 - 309 Protein_34 recombinase family protein -
SBAL117_RS24410 30760..31083 + 324 WP_011840013.1 hypothetical protein -
SBAL117_RS24415 31126..31761 + 636 WP_011840014.1 SDR family NAD(P)-dependent oxidoreductase -
SBAL117_RS24420 32025..32636 + 612 WP_014620447.1 recombinase family protein -
SBAL117_RS24425 32854..33264 + 411 WP_006087348.1 hypothetical protein Antitoxin
SBAL117_RS24430 33261..34202 + 942 WP_014620448.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
SBAL117_RS24435 34210..36801 + 2592 WP_014620449.1 type I restriction-modification system subunit M -
SBAL117_RS25280 36803..37969 + 1167 WP_014620450.1 restriction endonuclease subunit S -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..71173 71173


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 314 a.a.        Molecular weight: 35799.78 Da        Isoelectric Point: 7.0963

>T27069 WP_014620448.1 NC_017578:33261-34202 [Shewanella baltica OS117]
MKKLKQQFLEVSDALALGNPAIIEKDYWVVALLSELEQLTFETHQMVFSGGTALAKSNVKILRMSEDVDIKLIPTPQFQH
LSRGRKKQYRKALAVQIETAIIASNKFSIEARLVQDEYRYVEYELKYPQQFSQAPCLRPIIKLELMETIPLLALETRGIQ
SLVAELYKLPQEVNGFICVSVNTTLVEKVLSMLRRTMSVKRDAARNDDVTLIRHIYDVHCIHAALALDNKLLAPLFLAVL
AEDIARFGNQHAEFVMDPTNELRLGLLELENNPLFRQRFDDFVKPMVFNSQSPNFDTCFMSFKHIATSLILTI

Download         Length: 942 bp

>T27069 NC_017578:33261-34202 [Shewanella baltica OS117]
ATGAAAAAACTGAAACAACAGTTCTTAGAGGTTTCCGATGCATTAGCGCTCGGGAACCCCGCCATAATTGAAAAAGATTA
TTGGGTGGTTGCTCTACTTTCAGAGCTTGAACAGCTAACGTTTGAAACTCATCAAATGGTGTTTTCCGGCGGCACCGCAC
TTGCTAAGTCCAATGTTAAAATACTTCGAATGTCTGAAGACGTGGACATAAAGCTGATCCCCACGCCGCAATTTCAACAC
CTTAGTCGCGGCAGGAAAAAACAGTACCGTAAAGCGTTAGCAGTACAAATTGAAACAGCGATTATTGCATCTAACAAATT
TTCTATCGAAGCTAGATTAGTTCAGGATGAATATCGCTATGTGGAATATGAGCTTAAATATCCACAACAATTTAGCCAGG
CTCCTTGTCTACGCCCAATCATCAAGTTAGAACTGATGGAGACAATTCCACTTCTTGCGCTGGAAACACGGGGCATTCAA
TCGTTAGTAGCAGAACTTTATAAGCTGCCACAAGAAGTGAACGGATTCATCTGTGTATCAGTAAATACCACCTTGGTGGA
GAAAGTGCTTTCCATGCTACGCCGTACAATGTCAGTTAAGCGTGATGCAGCGCGAAACGATGACGTCACCTTAATTCGAC
ATATTTACGACGTACACTGTATTCATGCAGCACTGGCCCTTGATAATAAATTACTCGCGCCCCTTTTCCTCGCCGTATTA
GCAGAAGATATTGCTCGCTTTGGCAACCAACATGCCGAATTCGTCATGGACCCAACCAATGAGTTACGCCTTGGCTTACT
GGAGCTAGAAAACAACCCACTCTTCCGACAACGCTTTGATGATTTTGTTAAACCAATGGTGTTTAACTCGCAATCACCCA
ATTTTGATACGTGCTTTATGTCCTTTAAACATATTGCGACATCACTCATTCTGACTATTTAG

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 15505.88 Da        Isoelectric Point: 10.3652

>AT27069 WP_006087348.1 NC_017578:32854-33264 [Shewanella baltica OS117]
MAAVDSIFQKIKRSRRYVFERKDFDGIASYDQIGRSLNQLMDRGEIMKLGYGLYTKARVNSLTGRLMPTCPGGSDALMRE
ILKMKDIDFEIDNLSLQSLSGKNTQIPSSVHYSWDQKQFNRKLVVGNRLLTPASRP

Download         Length: 411 bp

>AT27069 NC_017578:32854-33264 [Shewanella baltica OS117]
ATGGCAGCTGTTGACAGTATCTTTCAAAAAATAAAGCGTTCTAGACGCTACGTTTTCGAACGCAAAGACTTTGACGGCAT
TGCTAGCTATGACCAGATTGGCAGATCGCTTAACCAGTTAATGGATAGAGGCGAGATAATGAAGCTTGGCTATGGCTTAT
ACACTAAAGCGCGAGTAAATAGCCTGACAGGACGTTTAATGCCGACCTGTCCAGGTGGTAGCGATGCACTTATGCGTGAA
ATATTGAAAATGAAAGACATCGATTTCGAGATAGATAATCTGTCCTTACAAAGTCTTTCCGGTAAAAACACCCAAATTCC
CTCATCAGTTCATTACTCATGGGATCAAAAACAGTTCAATCGAAAATTGGTTGTTGGTAACAGACTGTTGACGCCAGCAA
GTAGACCATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7U4E3J6


Antitoxin

Source ID Structure
AlphaFold DB A3DB89

References